Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks
occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever …

Filoviruses, including Ebolavirus and Marburgvirus, pose significant threats to public health
and species conservation by causing hemorrhagic fever outbreaks with high mortality rates …

Filovirus infections can cause a severe and often fatal disease in humans and nonhuman
primates, including great apes. Here, three anti-Ebola virus mouse/human chimeric mAbs …

Vaccines and therapies are urgently needed to address public health needs stemming from
emerging pathogens and biological threat agents such as the filoviruses Ebola virus (EBOV) …

Ebola virus (EBOV) infection blocks cellular production of alpha/beta interferon (IFN-α/β) and
the ability of cells to respond to IFN-α/β or IFN-γ. The EBOV VP35 protein has previously …

The Ebola virus VP35 protein was previously found to act as an interferon (IFN) antagonist
which could complement growth of influenza delNS1 virus, a mutant influenza virus lacking …

Replication-competent recombinant vesicular stomatitis viruses (rVSVs) expressing the type
I transmembrane glycoproteins and selected soluble glycoproteins of several viral …

Summary Background Infection with the Ebola virus induces overexpression of the
procoagulant tissue factor in primate monocytes and macrophages, suggesting that …

The agents causing viral hemorrhagic fever (VHF) are a taxonomically diverse group of
viruses that may share commonalities in the process whereby they produce systemic and …

Disseminated intravascular coagulation is a prominent manifestation of Ebola virus (EBOV)
infection. Here, we report that tissue factor (TF) plays an important role in triggering the …