[HTML][HTML] Molecular determinants of Ebola virus virulence in mice

H Ebihara, A Takada, D Kobasa, S Jones… - PLoS …, 2006 - journals.plos.org
Zaire ebolavirus (ZEBOV) causes severe hemorrhagic fever in humans and nonhuman
primates, with fatality rates in humans of up to 90%. The molecular basis for the extreme …

Ebola virus pathogenesis: implications for vaccines and therapies

N Sullivan, ZY Yang, GJ Nabel - Journal of virology, 2003 - Am Soc Microbiol
Ebola virus is an aggressive pathogen that causes a highly lethal hemorrhagic fever
syndrome in humans and nonhuman primates. First recognized near the Ebola River valley …

Characterization of the glycoproteins of Crimean-Congo hemorrhagic fever virus

AJ Sanchez, MJ Vincent, ST Nichol - Journal of virology, 2002 - Am Soc Microbiol
Crimean-Congo hemorrhagic fever (CCHF) virus is the cause of an important tick-borne
disease of humans throughout regions of Africa, Europe, and Asia. Like other members of …

Antibody-dependent enhancement of Ebola virus infection

A Takada, H Feldmann, TG Ksiazek… - Journal of virology, 2003 - Am Soc Microbiol
Most strains of Ebola virus cause a rapidly fatal hemorrhagic disease in humans, yet there
are still no biologic explanations that adequately account for the extreme virulence of these …

Inhibition of filovirus replication by the zinc finger antiviral protein

S Müller, P Möller, MJ Bick, S Wurr, S Becker… - Journal of …, 2007 - Am Soc Microbiol
The zinc finger antiviral protein (ZAP) was recently shown to inhibit Moloney murine
leukemia virus and Sindbis virus replication. We tested whether ZAP also acts against Ebola …

[HTML][HTML] Ebola and Marburg haemorrhagic fever viruses: major scientific advances, but a relatively minor public health threat for Africa

EM Leroy, JP Gonzalez, S Baize - Clinical Microbiology and Infection, 2011 - Elsevier
Ebola and Marburg viruses are the only members of the Filoviridae family (order
Mononegavirales), a group of viruses characterized by a linear, non-segmented, single …

Viral hemorrhagic fever–a vascular disease?

HJ Schnittler, H Feldmann - Thrombosis and haemostasis, 2003 - thieme-connect.com
The syndrome of “viral hemorrhagic fever” in man caused by certain viruses, such as Ebola,
Lassa, Dengue, and Crimean-Congo hemorrhagic fever viruses, is often associated with a …

Ebola virus: unravelling pathogenesis to combat a deadly disease

T Hoenen, A Groseth, D Falzarano… - Trends in molecular …, 2006 - cell.com
Ebola virus (EBOV) causes severe haemorrhagic fever leading to up to 90% lethality.
Increasingly frequent outbreaks and the placement of EBOV in the category A list of potential …

[HTML][HTML] Assembly and Budding of Ebolavirus

T Noda, H Ebihara, Y Muramoto, K Fujii… - PLoS …, 2006 - journals.plos.org
Ebolavirus is responsible for highly lethal hemorrhagic fever. Like all viruses, it must
reproduce its various components and assemble them in cells in order to reproduce …

Effects of Ebola virus glycoproteins on endothelial cell activation and barrier function

VM Wahl-Jensen, TA Afanasieva, J Seebach… - Journal of …, 2005 - Am Soc Microbiol
Ebola virus causes severe hemorrhagic fever with high mortality rates in humans and
nonhuman primates. Vascular instability and dysregulation are disease-decisive symptoms …