[HTML][HTML] Mucins and pathogenic mucin-like molecules are immunomodulators during infection and targets for diagnostics and vaccines

S Pinzón Martín, PH Seeberger, D Varón Silva - Frontiers in chemistry, 2019 - frontiersin.org
Mucins and mucin-like molecules are highly O-glycosylated proteins present on the cell
surface of mammals and other organisms. These glycoproteins are highly diverse in the …

Role of lipid rafts in virus replication

A Ono, EO Freed - Advances in virus research, 2005 - Elsevier
Publisher Summary This chapter illustrates the current knowledge on lipid rafts and
describes the most recent findings on the relationship between lipid rafts and virus …

Production of novel Ebola virus-like particles from cDNAs: an alternative to Ebola virus generation by reverse genetics

S Watanabe, T Watanabe, T Noda, A Takada… - Journal of …, 2004 - Am Soc Microbiol
We established a plasmid-based system for generating infectious Ebola virus-like particles
(VLPs), which contain an Ebola virus-like minigenome consisting of a negative-sense copy …

[HTML][HTML] Using a mHealth tutorial application to change knowledge and attitude of frontline health workers to Ebola virus disease in Nigeria: a before-and-after study

A Otu, B Ebenso, O Okuzu, E Osifo-Dawodu - Human resources for health, 2016 - Springer
Abstract Background The Ebola epidemic exposed the weak state of health systems in West
Africa and their devastating effect on frontline health workers and the health of populations …

[HTML][HTML] A C-terminal basic amino acid motif of Zaire ebolavirus VP35 is essential for type I interferon antagonism and displays high identity with the RNA-binding …

AL Hartman, JS Towner, ST Nichol - Virology, 2004 - Elsevier
The ebolavirus VP35 protein antagonizes the cellular type I interferon response by blocking
phosphorylation of IRF-3, a transcription factor that turns on the expression of a large …

Spatio‐temporal dynamics of pneumonia in bighorn sheep

EF Cassirer, RK Plowright, KR Manlove… - Journal of Animal …, 2013 - Wiley Online Library
Bighorn sheep mortality related to pneumonia is a primary factor limiting population recovery
across western North America, but management has been constrained by an incomplete …

Inhibition of heat-shock protein 90 reduces Ebola virus replication

DR Smith, S McCarthy, A Chrovian, G Olinger… - Antiviral research, 2010 - Elsevier
Ebola virus (EBOV), a negative-sense RNA virus in the family Filoviridae, is known to cause
severe hemorrhagic fever in humans and other primates. Infection with EBOV causes a high …

Ebola virus (EBOV) VP24 inhibits transcription and replication of the EBOV genome

S Watanabe, T Noda, P Halfmann… - The Journal of …, 2007 - academic.oup.com
The roles of Ebola virus (EBOV) VP24 in nucleocapsid (NC) formation and the effect of VP24
on transcription and replication of the viral genome during NC formation remain unknown …

Role of Ebola virus secreted glycoproteins and virus-like particles in activation of human macrophages

V Wahl-Jensen, SK Kurz, PR Hazelton… - Journal of …, 2005 - Am Soc Microbiol
Ebola virus, a member of the family Filoviridae, causes one of the most severe forms of viral
hemorrhagic fever. In the terminal stages of disease, symptoms progress to hypotension …

Comparison of individual and combination DNA vaccines for B. anthracis, Ebola virus, Marburg virus and Venezuelan equine encephalitis virus

J Riemenschneider, A Garrison, J Geisbert, P Jahrling… - Vaccine, 2003 - Elsevier
Multiagent DNA vaccines for highly pathogenic organisms offer an attractive approach for
preventing naturally occurring or deliberately introduced diseases. Few animal studies have …