Starch inclusion complex for the encapsulation and controlled release of bioactive guest compounds
The linear component of starch, especially amylose, is capable of forming inclusion complex
(IC) with various small molecules. It could significantly modify the structure and properties of …
(IC) with various small molecules. It could significantly modify the structure and properties of …
Beyond silver sulfadiazine: A dive into more than 50 years of research and development on metal complexes of sulfonamides in medicinal inorganic chemistry
JHB Nunes, DH Nakahata, PP Corbi… - Coordination Chemistry …, 2023 - Elsevier
Sulfonamides revolutionized the treatment and management of bacterial infections. Prontosil
was the very first synthetic antibacterial agent ever used in the clinics and its metabolite …
was the very first synthetic antibacterial agent ever used in the clinics and its metabolite …
[HTML][HTML] Nimesulide linked acyl thioureas potent carbonic anhydrase I, II and α-glucosidase inhibitors: Design, synthesis and molecular docking studies
Molecular hybridization has emerged as an interesting strategy to improve the effectiveness
and the scope of well-known drugs. Nimesulide has been used as non-steroidal anti …
and the scope of well-known drugs. Nimesulide has been used as non-steroidal anti …
Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 …
XL Zhao, L Yu, SD Zhang, K Ping, HY Ni, XY Qin… - International …, 2020 - Elsevier
Phenolic acids are found in natural plants, such as caffeic acid, rosmarinic acid, and
chlorogenic acid. They have long been used as pharmacological actives, owing to their anti …
chlorogenic acid. They have long been used as pharmacological actives, owing to their anti …
Synthesis, anticancer and antitubercular properties of new chalcones and their nitrogen-containing five-membered heterocyclic hybrids bearing sulfonamide moiety
LF Castaño, J Quiroga, R Abonia, D Insuasty… - International Journal of …, 2022 - mdpi.com
A new series of sulfonamides, 8a-b, 10, 12, and 14a-b, were synthesized by N-sulfonation
reaction with sulfonyl chlorides 6a-b. Five new series of chalcone-sulfonamide hybrids (16 …
reaction with sulfonyl chlorides 6a-b. Five new series of chalcone-sulfonamide hybrids (16 …
Combining 3D printing and screen-printing in miniaturized, disposable sensors with carbon paste electrodes
EM Materon, A Wong, LM Gomes… - Journal of Materials …, 2021 - pubs.rsc.org
In this paper we report on a modular design that allows one to fabricate electrochemical
sensors upon combining 3D printing and screen printing. The usefulness of the design is …
sensors upon combining 3D printing and screen printing. The usefulness of the design is …
New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects
Seventeen new amide/sulfonamide containing nimesulide derivatives were synthesized and
characterized by several spectroscopic techniques and primarily investigated for their …
characterized by several spectroscopic techniques and primarily investigated for their …
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering
N Vunnam, MC Young, EE Liao, CH Lo… - Cancer Biology & …, 2023 - Taylor & Francis
Nimesulide is a nonsteroidal anti-inflammatory drug and a COX-2 inhibitor with antitumor
and antiproliferative activities that induces apoptosis in oral, esophagus, breast, and …
and antiproliferative activities that induces apoptosis in oral, esophagus, breast, and …
Development of nimesulide amorphous solid dispersions via supercritical anti-solvent process for dissolution enhancement
G Liu, L Gong, J Zhang, Z Wu, H Deng… - European Journal of …, 2020 - Elsevier
Formulating amorphous solid dispersions (ASDs) is one of the most promising strategies to
overcome solubility limitations in drug development. In this work, development of nimesulide …
overcome solubility limitations in drug development. In this work, development of nimesulide …
A review on developments and prospects of anti-inflammatory in microemulsions
LP Alves, K da Silva Oliveira… - Journal of Drug Delivery …, 2020 - Elsevier
Anti-inflammatory drugs often cause diverse side effects and have high lipophilicity,
therefore there is a need to search for new anti-inflammatory agents or new drug delivery …
therefore there is a need to search for new anti-inflammatory agents or new drug delivery …