Starch inclusion complex for the encapsulation and controlled release of bioactive guest compounds

L Shi, J Zhou, J Guo, I Gladden, L Kong - Carbohydrate Polymers, 2021 - Elsevier
The linear component of starch, especially amylose, is capable of forming inclusion complex
(IC) with various small molecules. It could significantly modify the structure and properties of …

Beyond silver sulfadiazine: A dive into more than 50 years of research and development on metal complexes of sulfonamides in medicinal inorganic chemistry

JHB Nunes, DH Nakahata, PP Corbi… - Coordination Chemistry …, 2023 - Elsevier
Sulfonamides revolutionized the treatment and management of bacterial infections. Prontosil
was the very first synthetic antibacterial agent ever used in the clinics and its metabolite …

[HTML][HTML] Nimesulide linked acyl thioureas potent carbonic anhydrase I, II and α-glucosidase inhibitors: Design, synthesis and molecular docking studies

A Ahmed, I Shafique, A Saeed, G Shabir… - European Journal of …, 2022 - Elsevier
Molecular hybridization has emerged as an interesting strategy to improve the effectiveness
and the scope of well-known drugs. Nimesulide has been used as non-steroidal anti …

Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 …

XL Zhao, L Yu, SD Zhang, K Ping, HY Ni, XY Qin… - International …, 2020 - Elsevier
Phenolic acids are found in natural plants, such as caffeic acid, rosmarinic acid, and
chlorogenic acid. They have long been used as pharmacological actives, owing to their anti …

Synthesis, anticancer and antitubercular properties of new chalcones and their nitrogen-containing five-membered heterocyclic hybrids bearing sulfonamide moiety

LF Castaño, J Quiroga, R Abonia, D Insuasty… - International Journal of …, 2022 - mdpi.com
A new series of sulfonamides, 8a-b, 10, 12, and 14a-b, were synthesized by N-sulfonation
reaction with sulfonyl chlorides 6a-b. Five new series of chalcone-sulfonamide hybrids (16 …

Combining 3D printing and screen-printing in miniaturized, disposable sensors with carbon paste electrodes

EM Materon, A Wong, LM Gomes… - Journal of Materials …, 2021 - pubs.rsc.org
In this paper we report on a modular design that allows one to fabricate electrochemical
sensors upon combining 3D printing and screen printing. The usefulness of the design is …

New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects

T Güngör, A Ozleyen, YB Yılmaz, P Siyah, M Ay… - European journal of …, 2021 - Elsevier
Seventeen new amide/sulfonamide containing nimesulide derivatives were synthesized and
characterized by several spectroscopic techniques and primarily investigated for their …

Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering

N Vunnam, MC Young, EE Liao, CH Lo… - Cancer Biology & …, 2023 - Taylor & Francis
Nimesulide is a nonsteroidal anti-inflammatory drug and a COX-2 inhibitor with antitumor
and antiproliferative activities that induces apoptosis in oral, esophagus, breast, and …

Development of nimesulide amorphous solid dispersions via supercritical anti-solvent process for dissolution enhancement

G Liu, L Gong, J Zhang, Z Wu, H Deng… - European Journal of …, 2020 - Elsevier
Formulating amorphous solid dispersions (ASDs) is one of the most promising strategies to
overcome solubility limitations in drug development. In this work, development of nimesulide …

A review on developments and prospects of anti-inflammatory in microemulsions

LP Alves, K da Silva Oliveira… - Journal of Drug Delivery …, 2020 - Elsevier
Anti-inflammatory drugs often cause diverse side effects and have high lipophilicity,
therefore there is a need to search for new anti-inflammatory agents or new drug delivery …