Blood biomarkers to predict the onset of pre-eclampsia: A systematic review and meta-analysis

M Danielli, RC Thomas, CL Gillies, J Hu, K Khunti… - Heliyon, 2022 - cell.com
Pre-eclampsia is one of the most common pregnancy complications, and a major cause of
fetal and maternal morbidity and mortality globally. Diagnosis currently takes place in the …

Influential Serum Kinases (Non-sFlt-1) and Phosphatases in Preeclampsia—Systematic Review and Metanalysis

KC Marrufo-Gallegos, JR Villafán-Bernal… - International Journal of …, 2023 - mdpi.com
The early identification of women with an increased risk of preeclampsia (PE) is desirable,
but apart from soluble fms-like tyrosine kinase-1 (sFlt-1), few biomarkers have previously …

Association between maternal exposure to per-and polyfluoroalkyl substances and serum markers of liver function during pregnancy in China: a mixture-based …

Q Liao, P Tang, H Fan, Y Song, J Liang, H Huang… - Environmental …, 2023 - Elsevier
Previous studies have shown that per-and polyfluoroalkyl substances (PFAS) may have
hepatotoxic effects in animals. However, epidemiological evidence in humans, especially …

Association of first trimester serum uric acid with preeclampsia: an observational cohort study with propensity score matching

C Yue, C Ying, X Li - Hypertension Research, 2023 - nature.com
To elucidate whether uric acid changes in early pregnancy are associated with the
development of preeclampsia and their association with preeclampsia-related adverse …

The Association between Gut Microbiome and Pregnancy-Induced Hypertension: A Nested Case–Control Study

H Lin, J Chen, S Ma, R An, X Li, H Tan - Nutrients, 2022 - mdpi.com
(1) Background: Pregnancy-induced hypertension (PIH) is associated with obvious
microbiota dysbiosis in the third trimester of pregnancy. However, the mechanisms behind …

High-normal liver enzyme levels in early pregnancy predispose the risk of gestational hypertension and preeclampsia: A prospective cohort study

Y Zhang, C Sheng, D Wang, X Chen, Y Jiang… - Frontiers in …, 2022 - frontiersin.org
Background Gestational hypertension (GH) and preeclampsia (PE) are severe adverse
gestational complications. Previous studies supported potential link between elevated liver …

Glucose transporter 9 (GLUT9) plays an important role in the placental uric acid transport system

BP Lüscher, C Albrecht, B Stieger, DV Surbek… - Cells, 2022 - mdpi.com
Background: Hyperuricemia is a common laboratory finding in pregnant women
compromised by preeclampsia. A growing body of evidence suggests that uric acid is …

Cardiac-targeted PIASy gene silencing mediates deSUMOylation of caveolin-3 and prevents ischemia/reperfusion-induced Nav1.5 downregulation and ventricular …

CC Hu, X Wei, JM Liu, LL Han, CK Xia, J Wu… - Military Medical …, 2022 - Springer
Abstract Background Abnormal myocardial Nav1. 5 expression and function cause lethal
ventricular arrhythmias during myocardial ischemia–reperfusion (I/R). Protein inhibitor of …

Cholelithiasis is an additional pre-pregnancy clinical risk factor for preeclampsia

S Arbuzova, M Nikolenko, D Wright… - Archives of Gynecology …, 2023 - Springer
Purpose To investigate additional potential clinical risk factors for preeclampsia. Methods
This is a nested case–control study of preeclampsia and unaffected pregnancies. Cases …

Associations of maternal liver biomarkers in the first trimester with the risk of hypertensive disorders of pregnancy

H Liu, L Zhang, D Ainiwan, P Chi, H Cheng… - Hypertension …, 2024 - nature.com
This study aimed to evaluate the association between maternal liver biomarkers in early
pregnancy and the risk of hypertensive disorders of pregnancy (HDP), as well as to evaluate …