Platinum-based chemotherapy is an effective treatment used in multiple tumor treatments,
but produces severe side effects including neurotoxicity, anemia, and immunosuppression …

Prostate cancer (PCa) is the second-leading cause of cancer-related mortality, after lung
cancer, in men from developed countries. In its early stages, primary tumor growth is …

Simple Summary The five-year survival rate for ovarian cancer is less than 50%, resulting in
a global burden of> 140,000 deaths annually. Late detection, cancer heterogeneity, and …

Pituitary adenylate cyclase-activating polypeptide (PACAP) is an autocrine growth factor for
some lung cancer cells. The activated PACAP receptor (PAC1) causes phosphatidylinositol …

Lung cancer kills approximately 1.3 million citizens in the world annually. The tyrosine
kinase inhibitors (TKI) erlotinib and gefitinib are effective anti-tumor agents especially in lung …

The worldwide prevalence of lung cancer is amongst the greatest of all cancers, and deaths
due to lung cancer are the highest. Current researches are focusing on a molecular …

Approximately 50,000 new cases of head and neck squamous cell carcinoma (HNSCC) are
diagnosed worldwide each year and subsequently treated with surgery, chemotherapy …

Foregut neuroendocrine tumors [NETs] usually pursuit a benign course, but some show
aggressive behavior. The treatment of patients with advanced NETs is marginally effective …

Objective Epidermal growth factor (EGF) receptor (EGFR/HER1) is overexpressed in human
pancreatic cancers. However, anti-EGFR therapy does not exhibit significant therapeutic …

Our main objective was to search for mutations in candidate genes and for paired box gene
8–peroxisome proliferator-activated receptor gamma (PAX8–PPARγ) rearrangement in a …