Skin tests, including patch tests (PTs), prick tests, and intradermal tests (IDTs), are useful in
identifying the culprits of cutaneous adverse drug reactions (CADRs), and determining safer …

Mastocytosis is a neoplasm characterized by an accumulation of mast cells in various
organs and increased risk for severe anaphylaxis in patients with concomitant allergies …

In drug hypersensitivity, drug provocation testing (DPT), also called drug challenge, is the
gold standard for investigation. In recent years, risk stratification has become an important …

Diagnosing immediate drug hypersensitivity reactions (IDHRs) can pose a significant
challenge and there is an urgent need for safe and reliable tests. Evidence has emerged …

In the manuscript, a strong recommendation is indicated by the phrase “we recommend” and
a conditional or weakened recommendation is indicated by “we suggest”. An open …

At present, iodinated contrast media (ICM) are mostly non-ionic, have low osmolality, and
are safe. Even if adverse drug reactions (ADRs) occur, most are chemo-toxic symptoms and …

Purpose Covid-19 related lockdowns have resulted in a shortage of iodinated contrast
media (ICM) in 2022. Health care providers have reacted with implementing conservation …

Background The recurrence of hypersensitivity reaction (HSR) to low-osmolar iodinated
contrast media (LOCM) remains challenging despite premedication and substitution of the …

Drug hypersensitivity reactions (DHR) are heterogeneous in their pathomechanisms, clinical
presentation, severity, and outcomes. Novel DHR mechanisms, phenotypes, and endotypes …

Patch tests (PTs) and skin tests (STs), namely skin prick tests (SPTs) and intradermal tests
(IDTs), are useful tools for diagnosing drug hypersensitivity. They can be used to …