The multifaceted role of ferroptosis in liver disease
Ferroptosis is an iron-dependent form of non-apoptotic cell death characterized by
excessive lipid peroxidation and associated with a plethora of pathological conditions in the …
excessive lipid peroxidation and associated with a plethora of pathological conditions in the …
[PDF][PDF] Iron overload disorders
Iron overload disorders represent a variety of conditions that lead to increased total body
iron stores and resultant end‐organ damage. An elevated ferritin and transferrin‐iron …
iron stores and resultant end‐organ damage. An elevated ferritin and transferrin‐iron …
Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency
P Ponikowski, DJ Van Veldhuisen… - European heart …, 2015 - academic.oup.com
Aim The aim of this study was to evaluate the benefits and safety of long-term iv iron therapy
in iron-deficient patients with heart failure (HF). Methods and results CONFIRM-HF was a …
in iron-deficient patients with heart failure (HF). Methods and results CONFIRM-HF was a …
Targeting ferroptosis alleviates methionine‐choline deficient (MCD)‐diet induced NASH by suppressing liver lipotoxicity
X Li, TX Wang, X Huang, Y Li, T Sun, S Zang… - Liver …, 2020 - Wiley Online Library
Background NASH is one of the fastest growing liver diseases that leads to severe steatosis,
inflammation and ultimately liver injury. However, the pathophysiological mechanisms of …
inflammation and ultimately liver injury. However, the pathophysiological mechanisms of …
[HTML][HTML] Iron mediated toxicity and programmed cell death: A review and a re-examination of existing paradigms
Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells
DB Kell, E Pretorius - Metallomics, 2014 - academic.oup.com
Abstract" Serum ferritin" presents a paradox, as the iron storage protein ferritin is not
synthesised in serum yet is to be found there. Serum ferritin is also a well known …
synthesised in serum yet is to be found there. Serum ferritin is also a well known …
Hyperferritinemia—a clinical overview
M Sandnes, RJ Ulvik, M Vorland… - Journal of Clinical …, 2021 - mdpi.com
Ferritin is one of the most frequently requested laboratory tests in primary and secondary
care, and levels often deviate from reference ranges. Serving as an indirect marker for total …
care, and levels often deviate from reference ranges. Serving as an indirect marker for total …
Obesity as an emerging risk factor for iron deficiency
E Aigner, A Feldman, C Datz - Nutrients, 2014 - mdpi.com
Iron homeostasis is affected by obesity and obesity-related insulin resistance in a many-
facetted fashion. On one hand, iron deficiency and anemia are frequent findings in subjects …
facetted fashion. On one hand, iron deficiency and anemia are frequent findings in subjects …
[HTML][HTML] The role of iron and iron overload in chronic liver disease
The liver plays a major role in iron homeostasis; thus, in patients with chronic liver disease,
iron regulation may be disturbed. Higher iron levels are present not only in patients with …
iron regulation may be disturbed. Higher iron levels are present not only in patients with …
Benzoate and sorbate salts: a systematic review of the potential hazards of these invaluable preservatives and the expanding spectrum of clinical uses for sodium …
JD Piper, PW Piper - … reviews in food science and food safety, 2017 - Wiley Online Library
Sodium benzoate and potassium sorbate are extremely useful agents for food and beverage
preservation, yet concerns remain over their complete safety. Benzoate can react with the …
preservation, yet concerns remain over their complete safety. Benzoate can react with the …