[HTML][HTML] Is correction of iron deficiency a new addition to the treatment of the heart failure?

DS Silverberg, D Wexler, D Schwartz - International Journal of Molecular …, 2015 - mdpi.com
Anemia is present in about 40% of heart failure (HF) patients. Iron deficiency (ID) is present
in about 60% of the patients with anemia (about 24% of all HF patients) and in about 40% of …

[HTML][HTML] Matriptase-2 deficiency protects from obesity by modulating iron homeostasis

AR Folgueras, S Freitas-Rodríguez, AJ Ramsay… - Nature …, 2018 - nature.com
Alterations in iron status have frequently been associated with obesity and other metabolic
disorders. The hormone hepcidin stands out as a key regulator in the maintenance of iron …

[HTML][HTML] Recent advances in the application of ionomics in metabolic diseases

Y Zhang, B Huang, J Jin, Y Xiao, H Ying - Frontiers in Nutrition, 2023 - frontiersin.org
Trace elements and minerals play a significant role in human health and diseases. In recent
years, ionomics has been rapidly and widely applied to explore the distribution, regulation …

Bone marrow iron depletion is common in patients with coronary artery disease

EA Jankowska, K Wojtas, M Kasztura, G Mazur… - International journal of …, 2015 - Elsevier
Background/objectives Iron deficiency (ID) may be an important, treatable co-morbidity
complicating cardiovascular diseases, but considerable uncertainty exists about the …

Molecular pathogenesis and clinical consequences of iron overload in liver cirrhosis

K Sikorska, A Bernat, A Wróblewska - Hepatobiliary & Pancreatic Diseases …, 2016 - Elsevier
Background The liver, as the main iron storage compartment and the place of hepcidin
synthesis, is the central organ involved in maintaining iron homeostasis in the body …

The potential role of iron and copper in pediatric obesity and nonalcoholic fatty liver disease

A Feldman, E Aigner, D Weghuber… - BioMed research …, 2015 - Wiley Online Library
Obesity is a rapidly growing health problem and is paralleled by a multitude of comorbidities,
including nonalcoholic fatty liver disease (NAFLD). NAFLD has become the most common …

Crosstalk between intestinal flora and human iron metabolism: the role in metabolic syndrome-related comorbidities and its potential clinical application

Y Yan, W Zhang, Y Wang, C Yi, B Yu, X Pang, K Li… - Microbiological …, 2024 - Elsevier
The interaction of iron and intestinal flora, both of which play crucial roles in many
physiologic processes, is involved in the development of Metabolic syndrome (MetS). MetS …

[HTML][HTML] Hyperferritinemia and hypergammaglobulinemia predict the treatment response to standard therapy in autoimmune hepatitis

R Taubert, M Hardtke-Wolenski, F Noyan, C Lalanne… - PloS one, 2017 - journals.plos.org
Autoimmune hepatitis (AIH) is a chronic hepatitis with an increasing incidence. The majority
of patients require life-long immunosuppression and incomplete treatment response is …

[PDF][PDF] Co‐regulation of hepatic steatosis by ferritinophagy and unsaturated fatty acid supply

N Li, Y Liao, H Huang, S Fu - Hepatology Communications, 2022 - Wiley Online Library
Both iron overload and iron deficiency have been reported in obesity and metabolic
syndromes. Due to the presence of multiple intracellular iron pools and the dynamic nature …

Indoleamine 2, 3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis

C Wu, J Li, H Jia, J Zhao, M Qin, H Shi, C Liu… - Journal of …, 2024 - Springer
Background Non-alcoholic steatohepatitis (NASH) is a rapidly progressing chronic liver
disease of global significance. However, the underlying mechanisms responsible for NASH …