Gut liver brain axis in diseases: the implications for therapeutic interventions

M Yan, S Man, B Sun, L Ma, L Guo, L Huang… - Signal Transduction and …, 2023 - nature.com
Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

Neurodegenerative and neurodevelopmental diseases and the gut-brain axis: The potential of therapeutic targeting of the microbiome

B Bicknell, A Liebert, T Borody, G Herkes… - International journal of …, 2023 - mdpi.com
The human gut microbiome contains the largest number of bacteria in the body and has the
potential to greatly influence metabolism, not only locally but also systemically. There is an …

Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis

S Grabrucker, M Marizzoni, E Silajdžić, N Lopizzo… - Brain, 2023 - academic.oup.com
Alzheimer's disease is a complex neurodegenerative disorder leading to a decline in
cognitive function and mental health. Recent research has positioned the gut microbiota as …

Current discoveries and future implications of eating disorders

B Feng, J Harms, E Chen, P Gao, P Xu… - International Journal of …, 2023 - mdpi.com
Eating disorders (EDs) are characterized by severe disturbances in eating behaviors and
can sometimes be fatal. Eating disorders are also associated with distressing thoughts and …

Effects of the multidomain intervention with nutritional supplements on cognition and gut microbiome in early symptomatic Alzheimer's disease: a randomized …

EH Lee, GH Kim, HK Park, HJ Kang, YK Park… - Frontiers in Aging …, 2023 - frontiersin.org
Background The SoUth Korean study to PrEvent cognitive impaiRment and protect BRAIN
health through lifestyle intervention in at-risk elderly people (SUPERBRAIN) is a part of the …

Early Life Stress and Major Depressive Disorder—An Update on Molecular Mechanisms and Synaptic Impairments

AG Bertollo, ACL Galvan, C Dallagnol, AD Cortez… - Molecular …, 2024 - Springer
Early life stress (ELS), characterized as abuse, neglect, and abandonment, can cause
several adverse consequences in the lives of affected individuals. ELS experiences can …

The hypothalamic-pituitary-gonadal axis in men with schizophrenia

A Matuszewska, K Kowalski, P Jawień… - International Journal of …, 2023 - mdpi.com
Schizophrenia is a severe mental disorder with a chronic, progressive course. The etiology
of this condition is linked to the interactions of multiple genes and environmental factors. The …

[HTML][HTML] Exploring gender differences in the relationship between gut microbiome and depression-a scoping review

L Niemela, G Lamoury, S Carroll, M Morgia… - Frontiers in …, 2024 - frontiersin.org
Background Major depressive disorder (MDD) exhibits gender disparities, and emerging
evidence suggests the involvement of the gut microbiome, necessitating exploration of sex …

[HTML][HTML] Sex and gender as critical and distinct contributors to the human brain-gut-microbiome axis

NN Gancz, JA Levinson, BL Callaghan - Brain research bulletin, 2023 - Elsevier
The brain-gut-microbiome axis (BGMA) is a pivotal contributor to human health. A large body
of research, especially from animal models, has revealed bidirectional, causal relationships …

Do microbes play a role in Alzheimer's disease?

ZAP Williams, L Lang, S Nicolas, G Clarke… - Microbial …, 2024 - Wiley Online Library
Alzheimer's disease is a complex and progressive condition that affects essential
neurological functions such as memory and reasoning. In the brain, neuronal loss, synaptic …