Accumulating evidence shows that cellular and acellular components in tumor
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …

The treatment of advanced non-small cell lung cancer (NSCLC) may be changing, but the
cisplatin-based doublet remains the foundation of treatment for the majority of patients with …

Purpose To provide evidence-based recommendations to update the American Society of
Clinical Oncology guideline on systemic therapy for stage IV non–small-cell lung cancer …

It is clear that tumor cells do not act alone but in close interaction with the extracellular matrix
and with stromal cells in the tumor microenvironment (TME). As our understanding of tumor …

Background Systemic inflammation has been linked with cancer development, cancer
cachexia and poor outcome. Advanced lung cancer inflammation index (ALI) was developed …

Cancer therapy is a double-edged sword, as surgery and chemotherapy can induce an
inflammatory/immunosuppressive injury response that promotes dormancy escape and …

The clinical application of immunotherapy is the milestone of cancer treatment. However,
some patients have bad reaction. Cyclooxygenase-2 (COX-2) is frequently expressed in …

Cancer is not only composed malignant epithelial component but also stromal components
such as fibroblasts, endothelial cells, and inflammatory cells, by which an appropriate tumor …

Background Chemotherapy is a first-line treatment for advanced and metastatic bladder
cancer, but the unsatisfactory objective response rate to this treatment yields poor 5-year …

Abstract Cadmium ion (Cd 2+) exposure has been reported to associate with the prevalence
of dyslipidemia, and contribute to the initiation and progression of nonalcoholic fatty liver …