PURPOSE The overexpression of cyclooxygenase 2 (COX-2) gene, also known as
prostaglandin-endoperoxide synthase 2 (PTGS2), occurs in breast cancer, but whether it …

Disclosure: Dr. Hendriks reports no conflict of interest related to the current manuscript.
Outside of the current manuscript, Dr. Hendriks reports receiving research funding from …

Background Health-related quality of life (HRQoL) is recognized as a component endpoint
for cancer therapy approvals. The aim of this review was to evaluate the methodology of …

Background IL-1β is an essential factor of inflammation initiation, and it also promotes
malignant transformation, indicating its tumorigenic property. We aimed to investigate the …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality.
Curcumin is involved in various biological pathways leading to inhibition of NSCLC growth …

Abstract Ethnopharmacological relevance Saussurea laniceps Hand.-Mazz.(Compositae) is
a representative “snow lotus” herb well known in Chinese folk medicine to treat inflammation …

Cisplatin-based therapy is highly toxic, but moderately effective in most cancers. Concurrent
inhibition of cyclooxygenase-2 (COX-2) and soluble epoxide hydrolase (sEH) results in …

Background/Aims: IL-1β is an important mediator of “inflammation-cancer" transformation
through IL-1β/NF-κB/COX-2/HIF-1α signaling pathway, whereas certain portion of patients …

Knocking down delta-5-desaturase (D5D) expression by D5D small interfering RNA (siRNA)
has been reported that could redirect the cyclooxygenase-2 (COX-2)-catalyzed dihomo-γ …

Background Inflammation is closely related to cancer prognosis. The effect of celecoxib, a
nonsteroidal anti‐inflammatory drug, on the prognosis of patients with cancer remains …