Abstract Aim Cyclooxygenase‐2 (COX‐2) plays an important role in cell apoptosis,
angiogenesis and tumor invasion, and over‐expression of COX‐2 is associated with tumor …

Lung cancer is still an oncology challenge. A 5-year survival reaches less than 20% of
patients. Apoptosis disturbances are a key step in cancer development. The evaluation of …

The perioperative period of cancer surgery and its impact on patients' long-term cancer
outcomes is of increasing research interest. The physiological changes coincident with …

The treatment of lung cancer has seen significant advances in the last decade. A greater
understanding of the biology of tumors, and the development of advanced molecular …

An isocratic reversed phase HPLC method for the simultaneous determination of
doxorubicine (DOX) and celecoxib (CXB) out of a nanoparticulate fixed dose combination …

Background Progression-free survival (PFS) has not been validated as a surrogate endpoint
for overall survival (OS) in patients with advanced non-small cell lung cancer. Objective This …

Cancer and heart diseases are two of the major causes of death in the world. In the last few
decades, there is a rapid development in cancer therapies and early detection strategies …

Many of the physiological responses that comprise the surgical stress response are known
to promote cancer-signaling pathways. Tissue resection and exposure to the pharmaco …

Background: Non–small cell lung cancer (NSCLC) is the most common cause of cancer-
related mortality worldwide and represents a huge unmet medical need. Despite the …