This review summarizes the case for investing in adolescence as a period of rapid growth,
learning, adaptation, and formational neurobiological development. Adolescence is a …

Hormones regulate homeostasis by communicating through the bloodstream to the body's
organs, including the brain. As homeostatic regulators of brain function, some hormones …

When steroids, such as pregnenolone, progesterone and oestrogen, are synthesised de
novo in neural tissues, they are more specifically referred to as neurosteroids. These …

The potent estrogen 17β-Estradiol (E 2) plays a critical role in mediating hippocampal
function, yet the precise mechanisms through which E 2 enhances hippocampal memory …

Over the past two decades, the classical understanding of steroid action has been updated
to include rapid, membrane-initiated, neurotransmitter-like functions. While steroids were …

Multiple lines of evidence indicate that androgens, such as testosterone, modulate the
mesocorticolimbic system and executive function. This review integrates neuroanatomical …

This brief commentary reviews key steps in the history of steroid endocrinology that have
resulted in important conceptual shifts. Our understanding of the “Fast Effects of Steroids” …

Male-female interaction is important for finding a suitable mating partner and for ensuring
reproductive success. Male sexual signals such as pheromones transmit information and …

Beside their genomic mode of action, estrogens also activate a variety of cellular signaling
pathways through non-genomic mechanisms. Until recently, little was known regarding the …

Diverse cognitive functions in many vertebrate species are influenced by local conversion of
androgens to 17β-estradiol (E2) by aromatase. This enzyme is highly expressed in various …