Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non‐cardiac surgery

D Miller, SR Lewis, MW Pritchard… - Cochrane Database …, 2018 - cochranelibrary.com
Background The use of anaesthetics in the elderly surgical population (more than 60 years
of age) is increasing. Postoperative delirium, an acute condition characterized by reduced …

The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review

HK Fong, LP Sands, JM Leung - Anesthesia & Analgesia, 2006 - journals.lww.com
IMPLICATIONS: The current systematic review demonstrates that there are only a few
clinical trials that compare opioid analgesics or analgesic modalities. Meperidine appears to …

Deterioro cognitivo en el adulto mayor

CA Benavides-Caro - Revista Mexicana de anestesiología, 2017 - medigraphic.com
Introducción: El deterioro cognitivo del paciente anciano es un síndrome que lleva a un
aumento importante de costos sociales y económicos. Objetivos: Esta revisión de la …

Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar

V Jevtovic-Todorovic, AR Absalom… - British journal of …, 2013 - academic.oup.com
Although previously considered entirely reversible, general anaesthesia is now being
viewed as a potentially significant risk to cognitive performance at both extremes of age. A …

Postoperative cognitive dysfunction: incidence and prevention

LS Rasmussen - Best practice & research Clinical anaesthesiology, 2006 - Elsevier
Postoperative cognitive dysfunction (POCD) is a decline in cognitive function for weeks or
months after surgery. Due to its subtle nature, neuropsychological testing is necessary for its …

Neuroinflammation and cognitive function in aged mice following minor surgery

HA Rosczyk, NL Sparkman, RW Johnson - Experimental gerontology, 2008 - Elsevier
Following surgery, elderly patients often suffer from postoperative cognitive dysfunction
(POCD) which can persist long after physical recovery. It is known that surgery-induced …

Postoperative cognitive dysfunction after inhalational anesthesia in elderly patients undergoing major surgery: the influence of anesthetic technique, cerebral injury …

Y Qiao, H Feng, T Zhao, H Yan, H Zhang, X Zhao - BMC anesthesiology, 2015 - Springer
Background Elderly patients are reportedly at higher risk of postoperative cognitive
dysfunction (POCD) after inhalational anesthesia with sevoflurane. We hypothesized that the …

Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats

XZ Cao, H Ma, JK Wang, F Liu, BY Wu, AY Tian… - Progress in Neuro …, 2010 - Elsevier
Postoperative cognitive dysfunction (POCD) is characterized by the progressive
deterioration of intellectual/cognitive function following surgery. It has been suggested that …

Targeting neuroinflammation as a preventive and therapeutic approach for perioperative neurocognitive disorders

C Cheng, H Wan, P Cong, X Huang, T Wu… - Journal of …, 2022 - Springer
Perioperative neurocognitive disorders (PND) is a common postoperative complication
associated with regional or general anesthesia and surgery. Growing evidence in both …

An update on postoperative cognitive dysfunction

TL Tsai, LP Sands, JM Leung - Advances in anesthesia, 2010 - advancesinanesthesia.com
Postoperative cognitive dysfunction or decline (POCD) is increasingly recognized as a
common phenomenon after major surgery [1–4]. Because older age is a strong preoperative …