As the third most common malignancy and the second most deadly cancer, colorectal
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …

Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …

Rapid and efficient tools for early cancer detection have diagnostic and therapeutic value.
Given that the DNA hairpin‐based hybridization chain reaction (HCR) is effective in …

Remarkable progress has been made in the development of biomarker-driven targeted
therapies for patients with multiple cancer types, including melanoma, breast and lung …

PURPOSE BRAF V600E mutations are rarely associated with objective responses to the
BRAF inhibitor vemurafenib in patients with metastatic colorectal cancer (CRC). Blockade of …

Departments of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical
School, Tokyo, Japan Colorectal cancer (CRC) is the third most common cancer worldwide …

Immunotherapy has revolutionized colon cancer treatment. Immune checkpoint inhibitors
(ICIs) have shown clinical benefits for colon cancer patients, especially those with high …

Nanotechnology is reshaping health care strategies and is expected to exert a tremendous
impact in the coming years offering better healthcare facilities. It has led to not only …

Metastasis is a major cause of colorectal cancer (CRC) mortality, but its molecular
mechanisms are still not fully understood. Here, we show that upregulated DDX39B …

An increasing number of studies have shown that immunotherapy serves a significant role in
treating colorectal cancer (CRC) and has become a hotspot. However, few studies used the …