Selective COX-2 inhibitors: road from success to controversy and the quest for repurposing

AA El-Malah, MM Gineinah, PK Deb, AN Khayyat… - Pharmaceuticals, 2022 - mdpi.com
The introduction of selective COX-2 inhibitors (so-called 'coxibs') has demonstrated
tremendous commercial success due to their claimed lower potential of serious …

[HTML][HTML] Anticancer therapeutics: a brief account on wide refinements

FU Rehman, M Al-Waeel, SS Naz… - American Journal of …, 2020 - ncbi.nlm.nih.gov
The flustering rise in cancer incidence along with treatment anomalies has made cancer the
second leading cause of death globally. The total annual economic impact of cancer is …

The role of zyxin in carcinogenesis

A Partynska, A Gomulkiewicz, P Dziegiel… - Anticancer …, 2020 - ar.iiarjournals.org
Zyxin (ZYX) is a LIM domain protein whose presence has been detected in the cytoplasm
and nucleus. ZYX can translocate between these two compartments and therefore, can take …

ANALISIS KADAR CYCLOOXYGENASE-2 (COX-2) SERUM TERHADAP KESINTASAN PASIEN KANKER PARU JENIS KARSINOMA BUKAN SEL KECIL (KPKBSK) …

A Mustang - 2021 - repository.unhas.ac.id
Latar Belakang: Kanker paru merupakan penyebab utama kematian akibat kanker di dunia
termasuk di Indonesia. Penelitian menunjukkan tentang peran Cyclooxygenase-2 (COX-2) …