Poor water solubility of many drugs has emerged as one of the major challenges in the
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …

The pharmaceutical development of amorphous solid dispersions (ASDs) by hot-melt
extrusion (HME) is briefly reviewed. A systematic step-by-step approach is presented, where …

Abstract Purpose Amorphous solid dispersions (ASDs) have been widely used in the
pharmaceutical industry for solubility enhancementof poorly water-soluble drugs. The …

An industrially feasible approach to overcome the solubility and bioavailability limitations of
poorly soluble active pharmaceutical ingredients is the development of amorphous solid …

Co-amorphous drug delivery systems are evolving as a credible alternative to amorphous
solid dispersions technology. In Co-amorphous systems (CAMs), a drug is stabilized in …

Amorphous solid dispersion (ASD) formulation development is frequently difficult owing to
the inherent physical instability of the amorphous form, and limited understanding of the …

Amorphous solid dispersions (ASDs) have the potential to offer higher apparent solubility
and bioavailability of BCS class II drugs. Knowledge of the solid state drug-polymer …

The aim of this study was to develop self emulsifying drug delivery systems (SEDDS) of
glipizide and to convert it into solid SEDDS (S-SEDDS) using Syloid® 244 FP as adsorbent …

Purpose The study discusses the value of electrospun cilostazol-loaded (CIL) polymer
structures for potential vascular implant applications. Methods Biodegradable …

To improve solubility of tadalafil (Td), a poorly soluble drug substance (3 μg/ml) belonging to
the II class of the Biopharmaceutical Classification System, its six different solid dispersions …