[HTML][HTML] Review of the immune checkpoint inhibitors in the context of cancer treatment
NA Alturki - Journal of Clinical Medicine, 2023 - mdpi.com
Checkpoint proteins are an integral part of the immune system and are used by the tumor
cells to evade immune response, which helps them grow uncontrollably. By blocking these …
cells to evade immune response, which helps them grow uncontrollably. By blocking these …
[HTML][HTML] Current analysis of hypoxic-ischemic encephalopathy research issues and future treatment modalities
HQ She, YF Sun, L Chen, QX Xiao, BY Luo… - Frontiers in …, 2023 - frontiersin.org
Hypoxic-ischemic encephalopathy (HIE) is the leading cause of long-term neurological
disability in neonates and adults. Through bibliometric analysis, we analyzed the current …
disability in neonates and adults. Through bibliometric analysis, we analyzed the current …
[HTML][HTML] TrkB-mediated neuroprotection in female hippocampal neurons is autonomous, estrogen receptor alpha-dependent, and eliminated by testosterone: a …
V Chanana, D Zafer, DB Kintner… - Biology of sex …, 2024 - Springer
Background Neonatal hypoxia ischemia (HI) related brain injury is one of the major causes
of learning disabilities and memory deficits in children. In both human and animal studies …
of learning disabilities and memory deficits in children. In both human and animal studies …
[HTML][HTML] Burst-Suppression EEG Reactivity to Photic Stimulation—A Translational Biomarker in Hypoxic–Ischemic Brain Injury
AC Pâslaru, A Călin, VP Morozan, M Stancu, L Tofan… - Biomolecules, 2024 - mdpi.com
The reactivity of an electroencephalogram (EEG) to external stimuli is impaired in comatose
patients showing burst-suppression (BS) patterns following hypoxic–ischemic brain injury …
patients showing burst-suppression (BS) patterns following hypoxic–ischemic brain injury …
Changes of Oxidative Stress-Related Gene Expression in an in vitro Model of Neonatal Hypoxic-Ischemic Encephalopathy
Background: We recently demonstrated that oxygen-glucose deprivation (OGD) and
unconjugated bilirubin (UCB) can damage mature and immature organotypic hippocampal …
unconjugated bilirubin (UCB) can damage mature and immature organotypic hippocampal …
Research progress of neonatal hypoxic‐ischemic encephalopathy in nonhuman primate models
YH Guan, HS Zhou, BY Luo, S Hussain, LL Xiong - Ibrain, 2023 - Wiley Online Library
Neonatal hypoxic‐ischemic encephalopathy (HIE) is one of the important complications of
neonatal asphyxia, which not only leads to neurological disability but also seriously …
neonatal asphyxia, which not only leads to neurological disability but also seriously …
[HTML][HTML] Experimental modeling of damaging and protective hypoxia of the mammalian brain
DG Semenov, AV Belyakov, EA Rybnikova - Journal of Evolutionary …, 2022 - Springer
Currently, there is a new surge of interest in the problem of hypoxia, almost lost in recent
decades. Due to the fact that the circle of competent specialists in this field has significantly …
decades. Due to the fact that the circle of competent specialists in this field has significantly …
[HTML][HTML] Modeling central nervous system injury in vitro: current status and promising future strategies
The central nervous system (CNS) injury, which occurs because of mechanical trauma or
ischemia/hypoxia, is one of the main causes of mortality and morbidity in the modern society …
ischemia/hypoxia, is one of the main causes of mortality and morbidity in the modern society …
Human-Induced Pluripotent Stem Cell-Based Model of the Blood-Brain at 10 Years: A Retrospective on Past and Current Disease Models
AJ Al-Ahmad - Human iPSC-derived Disease Models for Drug …, 2023 - Springer
The initial discovery and derivation of induced pluripotent stem cells (iPSCs) by Yamanaka
and colleagues in 2006 revolutionized the field of personalized medicine, as it opened the …
and colleagues in 2006 revolutionized the field of personalized medicine, as it opened the …
Dried Blood Spot Metabolome Features of Ischemic–Hypoxic Encephalopathy: A Neonatal Rat Model
C Eldarov, N Starodubtseva, Y Shevtsova… - International Journal of …, 2024 - mdpi.com
Hypoxic–ischemic encephalopathy (HIE) is a severe neurological disorder caused by
perinatal asphyxia with significant consequences. Early recognition and intervention are …
perinatal asphyxia with significant consequences. Early recognition and intervention are …