Primary endpoint analysis of the multicentre phase II hypo-FLAME trial for intermediate and high risk prostate cancer
C Draulans, UA van der Heide, K Haustermans… - Radiotherapy and …, 2020 - Elsevier
Background and purpose Local recurrences after radiotherapy for prostate cancer (PCa)
often originate at the location of the macroscopic tumour (s). Since PCa cells are known to …
often originate at the location of the macroscopic tumour (s). Since PCa cells are known to …
1.5 T MR-guided and daily adapted SBRT for prostate cancer: feasibility, preliminary clinical tolerability, quality of life and patient-reported outcomes during treatment
F Alongi, M Rigo, V Figlia, F Cuccia, N Giaj-Levra… - Radiation …, 2020 - Springer
Abstract Background Unity Elekta is a unique magnetic resonance (MR)-linac that
conjugates a 1.5 Tesla MR unit with a 7 MV flattening filter free accelerator. A prospective …
conjugates a 1.5 Tesla MR unit with a 7 MV flattening filter free accelerator. A prospective …
MR-guided radiotherapy for prostate cancer
External beam radiotherapy remains the primary treatment modality for localized prostate
cancer. The radiobiology of prostate carcinoma lends itself to hypofractionation, with recent …
cancer. The radiobiology of prostate carcinoma lends itself to hypofractionation, with recent …
Patterns of failure following external beam radiotherapy with or without an additional focal boost in the randomized controlled FLAME trial for localized prostate cancer
VH Groen, K Haustermans, FJ Pos, C Draulans… - European Urology, 2022 - Elsevier
Background Focal dose escalation in external beam radiotherapy (EBRT) showed an
increase in 5-yr biochemical disease-free survival in the Focal Lesion Ablative Microboost in …
increase in 5-yr biochemical disease-free survival in the Focal Lesion Ablative Microboost in …
Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model
Y Philippou, HT Sjoberg, E Murphy, S Alyacoubi… - British journal of …, 2020 - nature.com
Background Radiotherapy enhances innate and adaptive anti-tumour immunity. It is unclear
whether this effect may be harnessed by combining immunotherapy with radiotherapy …
whether this effect may be harnessed by combining immunotherapy with radiotherapy …
[HTML][HTML] Cone-beam computed tomography-guided online adaptive radiotherapy is feasible for prostate cancer patients
LGM Zwart, F Ong, LA Ten Asbroek… - Physics and Imaging in …, 2022 - Elsevier
Background and purpose Studies have shown the potential of cone-beam computed
tomography (CBCT)-guided online adaptive radiotherapy (oART) for prostate cancer …
tomography (CBCT)-guided online adaptive radiotherapy (oART) for prostate cancer …
The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy
A Ali, B Mekhaeil, OD Biziotis, EE Tsakiridis… - Communications …, 2023 - nature.com
Radiotherapy is a non-invasive standard treatment for prostate cancer (PC). However, PC
develops radio-resistance, highlighting a need for agents to improve radiotherapy response …
develops radio-resistance, highlighting a need for agents to improve radiotherapy response …
Safety and efficacy of virtual prostatectomy with single-dose radiotherapy in patients with intermediate-risk prostate cancer: results from the PROSINT phase 2 …
C Greco, O Pares, N Pimentel, V Louro… - JAMA …, 2021 - jamanetwork.com
Importance Ultra-high single-dose radiotherapy (SDRT) represents a potential alternative to
curative extreme hypofractionated stereotactic body radiotherapy (SBRT) in organ-confined …
curative extreme hypofractionated stereotactic body radiotherapy (SBRT) in organ-confined …
[HTML][HTML] Ginsenosides in cancer: A focus on the regulation of cell metabolism
W Yao, Y Guan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Metabolic alterations play a key role in promoting tumor initiation and progression, leading
to extensive tumor heterogeneity and adaptability. Thus, targeting abnormal metabolic …
to extensive tumor heterogeneity and adaptability. Thus, targeting abnormal metabolic …
[HTML][HTML] Quality-of-life outcomes and toxicity profile among patients with localized prostate cancer after radical prostatectomy treated with stereotactic body radiation …
TM Ma, LK Ballas, H Wilhalme, A Sachdeva… - International Journal of …, 2023 - Elsevier
Purpose Postoperative radiation therapy (RT) is an underused standard-of-care intervention
for patients with prostate cancer and recurrence/adverse pathologic features after radical …
for patients with prostate cancer and recurrence/adverse pathologic features after radical …