More than 40% of men with intermediate-risk or high-risk prostate cancer will experience a
biochemical recurrence after radical prostatectomy. Clinical guidelines for the management …

Radiation therapy has been used worldwide for many decades as a therapeutic regimen for
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …

The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

Hypofractionated radical radiotherapy is now an accepted standard of care for tumour sites
such as prostate and breast cancer. Much research effort is being directed towards more …

External beam radiotherapy is an effective curative treatment option for localized prostate
cancer, the most common cancer in men worldwide. However, conventionally fractionated …

Purpose Doses delivered to the urethra have been associated with an increased risk to
develop long-term urinary toxicity in patients undergoing stereotactic body radiotherapy …

Background Stereotactic body radiotherapy (SBRT) is becoming increasingly used in
treating localized prostate cancer (PCa), with evidence showing similar toxicity and efficacy …

Background The assessment of organ motion is a crucial feature for prostate stereotactic
body radiotherapy (SBRT). Rectal spacer may represent a helpful device in order to …

Urinary toxicity is common following pelvic radiotherapy and can have a substantial negative
effect on survivorship. Due to its prevalence and the increasing number of related clinical …

Background and purpose Interfraction volumetric changes/rotations in the prostate and
proximal seminal vesicles (SVs) might compromise target coverage when tight margins are …