It is well admitted that the link between chronic inflammation and cancer involves cytokines
and mediators of inflammatory pathways, which act during the different steps of …

Abstract Prostaglandin E2 (PGE2) and F2α (PGF2α) are the two most prominent prostanoids
in parturition. They are involved in cervical ripening, membrane rupture, myometrial …

Background Used alone, the MAS5. 0 algorithm for generating expression summaries has
been criticized for high False Positive rates resulting from exaggerated variance at low …

For more than a century, inhibition of prostaglandin biosynthesis via inhibition of the fatty
acid cyclooxygenase (COX) has been achieved by non-steroidal anti-inflammatory drugs …

Kaposi's sarcoma (KS), an enigmatic endothelial cell vascular neoplasm, is characterized by
the proliferation of spindle shaped endothelial cells, inflammatory cytokines (ICs), growth …

Endothelial cells play an active role in the maintenance of homeostasis. Endothelial injury
can give rise to endothelial dysfunction in which the profile of mediators released by …

Lung cancer is the most common cause of cancer-related death, with non-small-cell lung
cancer (NSCLC) accounting for 80%–85% of all cases. Although survival rates are …

The biological role of COX-2, the inducible form of cyclooxygenase, is to convert arachidonic
acid into prostaglandins (PGs) and thromboxanes (TXs). Overexpressed in many tumors …

Radiotherapy alone or in combination with chemotherapy/surgery is widely used for
treatment of cancers. It reduces tumor growth and prevents metastasis. While ionizing …

Abstract Prostaglandin E 2 (PGE 2) interacts with tyrosine kinases receptor signaling in both
tumor and stromal cells supporting tumor progression. Here we demonstrate that in non …