Chemical pleurodesis is a therapeutic procedure applied to create the symphysis between
the parietal and visceral pleura by intrapleural administration of various chemical agents (eg …

Notch signaling is an evolutionarily conserved cell–cell communication mechanism that
plays a key role in lung homeostasis, injury and repair. The loss of regulation of Notch …

Background: Lung cancer is associated with a high mortality rate and often complicated with
malignant pleural effusion (MPE), which has a very poor clinical outcome with a short life …

Increased abundance of polo-like kinase 1 (PLK1) is observed in various tumor types,
particularly in lung adenocarcinoma (LUAD). Here, we found that PLK1 accelerated the …

Malignant mesothelioma is an aggressive and lethal asbestos-related disease. Diagnosis of
malignant mesothelioma is particularly challenging and is further complicated by the lack of …

Abstract Background and Objective Checkpoint inhibitor-related pneumonitis (CIP) is one of
the most common serious and fatal adverse events associated with immune checkpoint …

There are two major groups of lung cancer: non-small cell lung cancer (NSCLC) and small
cell lung cancer (SCLC). NSCLCs can be further separated into three different categories …

Intra-operative photodynamic therapy (IO-PDT) in combination with surgery for the treatment
of non-small cell lung cancer and malignant pleural mesothelioma has shown promise in …

Malignant pleural effusion (MPE) is an important hallmark for late-stage lung cancer with
metastasis. Current clinical diagnosis methods require tedious work to distinguish MPE from …

Tumor-derived exosomes can modulate the cancer microenvironment and induce metastatic
spread. Exosomes may carry enzymes for leukotriene (LT) biosynthesis, but the role of …