Role of the innate and adaptive immune responses in the course of multiple sclerosis

B Hemmer, M Kerschensteiner, T Korn - The Lancet Neurology, 2015 - thelancet.com
Multiple sclerosis is a chronic disease of the CNS that leads to substantial disability in most
patients. The early phase is characterised by relapses and the later phase by progressive …

Vitamin D and multiple sclerosis

A Ascherio, KL Munger, KC Simon - The Lancet Neurology, 2010 - thelancet.com
The hypothesis that adequate vitamin D nutrition can contribute to the prevention of multiple
sclerosis (MS) was originally proposed to explain the geographical distribution of MS, but …

1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A

S Joshi, LC Pantalena, XK Liu, SL Gaffen… - … and cellular biology, 2011 - Taylor & Francis
A new class of inflammatory CD4+ T cells that produce interleukin-17 (IL-17)(termed Th17)
has been identified, which plays a critical role in numerous inflammatory conditions and …

The implication of vitamin D and autoimmunity: a comprehensive review

CY Yang, PSC Leung, IE Adamopoulos… - Clinical reviews in …, 2013 - Springer
Historically, vitamin D has been associated with the regulation of bone metabolism.
However, increasing evidence demonstrates a strong association between vitamin D …

Vitamin D in systemic and organ-specific autoimmune diseases

N Agmon-Levin, E Theodor, RM Segal… - Clinical reviews in allergy …, 2013 - Springer
Lately, vitamin D has been linked with metabolic and immunological processes, which
established its role as an essential component of human health preservation. Vitamin D has …

[HTML][HTML] Association of vitamin D metabolism gene polymorphisms with autoimmunity: evidence in population genetic studies

AI Ruiz-Ballesteros, MR Meza-Meza… - International journal of …, 2020 - mdpi.com
A high prevalence of vitamin D (calcidiol) serum deficiency has been described in several
autoimmune diseases, including multiple sclerosis (MS), rheumatoid arthritis (AR), and …

[HTML][HTML] Environmental risk factors for multiple sclerosis: a review with a focus on molecular mechanisms

C O'Gorman, R Lucas, B Taylor - International journal of molecular …, 2012 - mdpi.com
Multiple sclerosis (MS) is a chronic disabling disease of the central nervous system
commonly affecting young adults. Pathologically, there are patches of inflammation …

Vitamin D and genetic susceptibility to multiple sclerosis

C Scazzone, L Agnello, G Bivona, B Lo Sasso… - Biochemical …, 2021 - Springer
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system
(CNS), resulting from the interaction among genetic, epigenetic, and environmental factors …

Vitamin D and innate and adaptive immunity

M Hewison - Vitamins & hormones, 2011 - Elsevier
In the last 5 years there has been renewed interest in the health benefits of vitamin D. A
central feature of this revival has been new information concerning the nonclassical effects …

Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy

CM Lange, J Bojunga, E Ramos-Lopez… - Journal of …, 2011 - Elsevier
BACKGROUND & AIMS: Vitamin D is an important immune modulator and preliminary data
indicated an association between vitamin D deficiency and sustained virologic response …