Diabetic nephropathy (DN) is characterized by proliferation of mesangial cells, mesangial
hypertrophy and extracellular matrix (ECM) accumulation. Our recent study found that …

Chronic liver diseases, primarily metabolic dysfunction-associated steatotic liver disease
(MASLD), harmful use of alcohol, or viral hepatitis, may result in liver fibrosis, cirrhosis, and …

Pulmonary fibrosis is a relatively rare but devastating disease characterized by the
excessive deposition of extracellular matrix. The increased matrix results in reduced lung …

Abstract Aquaporin 3 (AQP3) is a transporter of water, glycerol and hydrogen peroxide
(H2O2) that is expressed in various epithelial cells and in macrophages. Here, we …

Differentiation of fibroblasts to myofibroblasts is governed by the transforming growth factor
beta (TGF-β) through a mechanism involving redox signaling and generation of reactive …

The aim of this work was to develop an individualized score for predicting hepatocellular
carcinoma (HCC) in patients with hepatitis C (HCV)‐compensated cirrhosis. Among 1,323 …

Hepatocellular carcinoma (HCC) is the fifth most common cancer, and hepatitis C virus
(HCV) infection plays a major role in HCC development. The molecular mechanisms by …

Accumulating evidence identifies autophagy as an inflammation-related defensive
mechanism against diseases including liver fibrosis. Therefore, autophagy may represent a …

Chronic liver disease (CLD) constitutes a growing global health issue, with no effective
treatments currently available. Oxidative stress closely interacts with other cellular and …

Background The potential of time-dependent diffusion MRI in imaging the progression from
liver fibrosis to cirrhosis has not been established. Purpose To assess the effectiveness of …