The development of novel therapeutics for the effective management of Parkinson's disease
(PD) is undertaken seriously by the scientific community as the burden of PD continues to …

α‐Synuclein (αS) is a key molecule in the pathomechanism of Parkinson's disease. Most
studies on αS to date have focused on its function in the neuronal cytosol, but its action in …

Abstract αSynuclein (αSyn) misfolding and aggregation frequently precedes neuronal loss
associated with Parkinson's Disease (PD) and other Synucleinopathies. The progressive …

The Parkinson's disease (PD) associated protein, alpha-synuclein (α-syn/SNCA), is highly
expressed in aggressive melanomas. The goal of this study was to reveal possible …

Alzheimer's disease (AD) is a prevalent type of dementia in elderly populations with a
significant genetic component. The accumulating evidence suggests that AD involves a …

(1) Background: Parkinson's disease (PD) is the most common movement disorder.
Imbalanced protein homeostasis and α-syn aggregation are involved in PD pathogenesis …

Epidemiological evidence points to an inverse association between Parkinson's disease
(PD) and almost all cancers except melanoma, for which this association is positive. The …

Neurodegenerative diseases have a complex origin and are composed of genetic and
environmental factors. Both DNA damage and chromatin rearrangement are important …

Parkinson's disease (PD), multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS)
are examples of neurodegenerative movement disorders (NMDs), which are defined by a …

We explored differences in the DNA methylation statuses of PSMA6, PSMB5, HIF1A, and
KEAP1 gene promoter regions in patients with type 1 diabetes and different diabetic …