Benefits and adverse events of melatonin use in the elderly

L Anghel, L Baroiu, CR Popazu… - Experimental and …, 2022 - spandidos-publications.com
Melatonin is a hormone secreted by the pineal gland in accordance with the circadian
rhythm when the light level decreases. Reduction of melatonin secretion with age may be …

The coronavirus disease 2019 (COVID-19): key emphasis on melatonin safety and therapeutic efficacy

E Ramos, F Lopez-Munoz, E Gil-Martin, J Egea… - Antioxidants, 2021 - mdpi.com
Viral infections constitute a tectonic convulsion in the normophysiology of the hosts. The
current coronavirus disease 2019 (COVID-19) pandemic is not an exception, and therefore …

[HTML][HTML] Computational study of the therapeutic potentials of a new series of imidazole derivatives against SARS-CoV-2

TO Johnson, AE Adegboyega, O Iwaloye… - Journal of …, 2021 - Elsevier
Owing to the urgent need for therapeutic interventions against the SARS-coronavirus 2
(SARS-CoV-2) pandemic, we employed an in silico approach to evaluate the SARS-CoV-2 …

Ultrasensitive and highly selective “turn-on” fluorescent sensor for the detection and measurement of melatonin in juice samples

EA Afshar, MA Taher, F Karimi, C Karaman, O Moradi - Chemosphere, 2022 - Elsevier
Melatonin (MLT), a hormone related to the regulation of brain functions, is directly related to
sleep quality and is considered to be a possible adjuvant therapy for patients needing …

Role of melatonin on virus-induced neuropathogenesis—a concomitant therapeutic strategy to understand SARS-CoV-2 infection

P Wongchitrat, M Shukla, R Sharma, P Govitrapong… - Antioxidants, 2021 - mdpi.com
Viral infections may cause neurological disorders by directly inducing oxidative stress and
interrupting immune system function, both of which contribute to neuronal death. Several …

Indole-based compounds as potential drug candidates for SARS-CoV-2

AS Girgis, SS Panda, BM Kariuki, MS Bekheit… - Molecules, 2023 - mdpi.com
The COVID-19 pandemic has posed a significant threat to society in recent times,
endangering human health, life, and economic well-being. The disease quickly spreads due …

Melatonin effect on platelets and coagulation: Implications for a prophylactic indication in COVID-19

A Hosseinzadeh, A Bagherifard, F Koosha, S Amiri… - Life Sciences, 2022 - Elsevier
Severe COVID-19 is associated with the dynamic changes in coagulation parameters.
Coagulopathy is considered as a major extra-pulmonary risk factor for severity and mortality …

Identification of lead compounds from large natural product library targeting 3C-like protease of SARS-CoV-2 using E-pharmacophore modelling, QSAR and …

OO Elekofehinti, O Iwaloye, OR Molehin… - In Silico …, 2021 - Springer
COVID-19 is a novel disease caused by SARS-CoV-2 and has made a catastrophic impact
on the global economy. As it is, there is no officially FDA approved drug to alleviate the …

SARS‐COV‐2 (COVID‐19): Cellular and biochemical properties and pharmacological insights into new therapeutic developments

H Parlakpinar, M Gunata - Cell Biochemistry and Function, 2021 - Wiley Online Library
COVID‐19 caused by SARS‐COV‐2 first appeared in the Wuhan City of China and began to
spread rapidly among people. Rapid progression of the outbreak has led to a major global …

Economic scar tissue of COVID-19 puzzle: An analysis, evidence and suggestion on global perspective

MS Hossain - Global business review, 2021 - journals.sagepub.com
The COVID-19 pandemic has instigated tremendous human and economic hardship around
the world. Using meta-literature and time series analysis, we conduct both synthesis and …