Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …

Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …

Simple Summary Tumor-Associated Macrophages (TAMs) play an important role in the
development of tumors, modulation of neoangiogenesis, immune suppression, and …

Escaping programmed cell death is a hallmark of cancer. NF-κB transcription factors are key
regulator of cell survival and aberrant NF-κB signaling has been involved in the …

Inflammation is an essential immune response that helps fight infections and heal tissues.
However, chronic inflammation has been linked to several diseases, including cancer …

Anthocyanins are flavonoid compounds that are abundantly present in fruits and vegetables.
These compounds contribute to the color of these foods and offer various health benefits to …

Many diseases, including cancer, stem from aberrant activation or overexpression of
oncoproteins that are associated with multiple signaling pathways. Although proteins with …

Fruits and vegetables are used not only for nutritional purposes but also as therapeutics to
treat various diseases and ailments. These food items are prominent sources of …

Iron-dependent lipid peroxidation causes ferroptosis, a form of regulated cell death. Crucial
steps in the formation of ferroptosis include the accumulation of ferrous ions (Fe2+) and lipid …

Glioblastoma multiforme (GBM) is the most aggressive type of primary brain tumor and is
associated with a poor clinical prognosis. Despite the progress in the understanding of the …