Abdominal aortic aneurysm (AAA), defined as a focal dilation of the abdominal aorta beyond
50% of its normal diameter, is a common and potentially life-threatening vascular disease …

Although inflammation plays critical roles in the development of atherosclerosis, its
regulatory mechanisms remain incompletely understood. Perivascular adipose tissue …

Aortic aneurysm and dissection (AAD) are a group of insidious and lethal cardiovascular
diseases that characterized by seriously threatening the life and health of people, but lack …

In Duchenne muscular dystrophy (DMD), a lack of functional dystrophin leads to myofiber
instability and progressive muscle damage that results in fibrosis. While fibrosis is primarily …

Cisplatin is widely used as an anti-tumor drug for the treatment of solid tumors.
Unfortunately, it causes kidney toxicity as a critical side effect, limiting its use, given that no …

The mechanistic basis for the formation of aortic aneurysms and dissection needs to be
elucidated to facilitate the development of effective medications. β-Aminopropionitrile …

Aim Doxorubicin, an anthracycline anti-tumour agent, is an essential chemotherapeutic
drug; however, the adverse events associated with doxorubicin usage, including …

Acute aortic dissection (AAD) is an acute inflammatory vascular condition associated with
significant morbidity and mortality. Depletion of neutrophils can attenuate the development …

Thoracic aortic dissection (TAD) is one of the most lethal aortic diseases due to its acute
onset, rapid progress, and high rate of aortic rupture. The pathogenesis of TAD is not …

Fewer females develop AADs (ascending aortic aneurysms and dissections) and the
reasons for this protection remain poorly understood. The present study seeks to develop a …