Peroxisome proliferator-activated receptors (PPARs), members of the nuclear receptor
superfamily, are important in whole-body energy metabolism. PPARs are classified into …

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor
superfamily that regulate the expression of genes related to lipid and glucose metabolism …

Background Hepatocellular carcinoma (HCC) is a common primary malignant tumor which
usually progresses to an advanced stage because of late diagnosis. Sorafenib (Sora) is a …

Intra-tumor heterogeneity contributes to treatment failure and poor survival in urothelial
bladder carcinoma (UBC). Analyzing transcriptome from a UBC cohort, we report that intra …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death due to its
early recurrence and widespread metastatic potential. Accumulating studies have reported …

ELF3 is one of the member of transcription factors from E-twenty-six family, its role varies in
different types of cancer. However, the role and specific mechanisms of ELF3 in the …

Regarding cancer as a genetic multi-factorial disease, a number of aspects need to be
investigated and analyzed in terms of cancer's predisposition, development and prognosis …

Nuclear receptors (NRs) are a superfamily of ligand-activated transcription factors that act as
biological sensors and use a combination of mechanisms to modulate positively and …

Hepatocellular carcinoma (HCC) has been extensively studied as one of the most
aggressive tumors worldwide. However, its mortality rate remains high due to ideal …

In this review study, we focus on potential benefits of the transcription factor PPARδ and its
ligand erucic acid (EA) in management of neuroectodermal tumors and Parkinson's …