Chemokines are a family of small, secreted cytokines which regulate a variety of cell
functions. The CXC motif chemokine ligand 12 (CXCL12) binds to CXC chemokine receptor …

The CXC chemokine CXCL12 is an important factor in physiological and pathological
processes, including embryogenesis, hematopoiesis, angiogenesis and inflammation …

As one of the most serious threats to human being, cancer is hard to be treated when
metastasis happens. What's worse, there are few identified targets of metastasis for drug …

The process of entering the bloodstream, intravasation, is a necessary step in the
development of distant metastases. The focus of this review is on the pathways and …

Chemokines are chemotactic cytokines that promote cancer growth, metastasis, and
regulate resistance to chemotherapy. Stromal cell-derived factor 1 (SDF1) also known as …

Non-small cell lung cancer (NSCLC) accounts for> 80% of lung cancer cases and currently
has an overall five-year survival rate of only 15%. Patients presenting with advanced stage …

Chemokines have fundamental roles in regulating immune and inflammatory responses,
primarily through their control of leukocyte migration and localization. The biological …

The directed migration of cell collectives is a driving force of embryogenesis,,. The
predominant view in the field is that cells in embryos navigate along pre-patterned …

Tumor metastases are responsible for approximately 90% of all cancer-related deaths.
Although many patients can be cured, in the US and UK, cancer still causes 730,000 deaths …

CXCL12 is a CXC chemokine that traditionally has been classified as a homeostatic
chemokine. It contributes to physiological processes such as embryogenesis, hematopoiesis …