Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

Stress, a ubiquitous part of daily human life, has varied biological effects which are
increasingly recognized as including modulation of commensal microorganisms residing in …

The importance of the gut–brain axis in regulating stress-related responses has long been
appreciated. More recently, the microbiota has emerged as a key player in the control of this …

Gut microbiome diversity has been strongly associated with mood-relating behaviours,
including major depressive disorder (MDD). This association stems from the recently …

Metabolomic analysis of human biospecimens had progressed quickly over the past
decade. Technological and methodological advances have led to the comprehensive …

The role of gut microbiota and its association with the central nervous system via the
microbiome-brain-gut axis has been widely discussed in the literature. The aim of this review …

The human gastrointestinal tract harbors most of the microbial cells inhabiting the body,
collectively known as the microbiota. These microbes have several implications for the …

Regulating fluctuating endogenous nitric oxide (NO) levels is necessary for proper
physiological functions. Aberrant NO pathways are implicated in a number of neurological …

Depression is a frequent mood disorder that might impair the brain-gut axis. In this study, we
divided 30 mice into five groups: untreated mice, mice with depression-like behaviors, mice …

Objective: Microbiota dysbiosis has been linked to major depressive disorder, but the
mechanisms whereby the microbiota modulates mood remain poorly understood. The …