Exosomes: key players in cancer and potential therapeutic strategy
J Dai, Y Su, S Zhong, L Cong, B Liu, J Yang… - Signal transduction and …, 2020 - nature.com
Exosomes are extracellular vesicles secreted by most eukaryotic cells and participate in
intercellular communication. The components of exosomes, including proteins, DNA, mRNA …
intercellular communication. The components of exosomes, including proteins, DNA, mRNA …
[HTML][HTML] Role of lncRNA LUCAT1 in cancer
C Xing, S Sun, ZQ Yue, F Bai - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Long non-coding RNAs (lncRNAs) are RNA molecules with a transcript length of more than
200 nt and lack a protein-coding ability. They regulate gene expression by interacting with …
200 nt and lack a protein-coding ability. They regulate gene expression by interacting with …
[HTML][HTML] Drug resistance and combating drug resistance in cancer
Cancer is the second leading cause of death in the US. Current major treatments for cancer
management include surgery, cytotoxic chemotherapy, targeted therapy, radiation therapy …
management include surgery, cytotoxic chemotherapy, targeted therapy, radiation therapy …
Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches
Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …
Long noncoding RNA in cancer: wiring signaling circuitry
C Lin, L Yang - Trends in cell biology, 2018 - cell.com
Long noncoding RNAs (lncRNAs), which are encoded by a vast less explored region of the
human genome, may hold missing drivers of cancer and have gained attention recently as a …
human genome, may hold missing drivers of cancer and have gained attention recently as a …
Role of non-coding RNAs and RNA modifiers in cancer therapy resistance
X Zhang, K Xie, H Zhou, Y Wu, C Li, Y Liu, Z Liu, Q Xu… - Molecular cancer, 2020 - Springer
As the standard treatments for cancer, chemotherapy and radiotherapy have been widely
applied to clinical practice worldwide. However, the resistance to cancer therapies is a major …
applied to clinical practice worldwide. However, the resistance to cancer therapies is a major …
The roles of exosomal miRNAs and lncRNAs in lung diseases
Y Li, Z Yin, J Fan, S Zhang, W Yang - Signal transduction and targeted …, 2019 - nature.com
An increasing number of studies have reported that exosomes released from various cells
can serve as mediators of information exchange between different cells. With further …
can serve as mediators of information exchange between different cells. With further …
LncRNA UCA1 promotes proliferation and cisplatin resistance of oral squamous cell carcinoma by sunppressing miR‐184 expression
Z Fang, J Zhao, W Xie, Q Sun, H Wang… - Cancer …, 2017 - Wiley Online Library
Chemotherapy resistance has become the main obstacle for the effective treatment of
human cancers. Long non‐coding RNA urothelial cancer associated 1 (UCA 1) is generally …
human cancers. Long non‐coding RNA urothelial cancer associated 1 (UCA 1) is generally …
The emerging role of lncRNAs in the regulation of cancer stem cells
R Castro-Oropeza, J Melendez-Zajgla, V Maldonado… - Cellular Oncology, 2018 - Springer
Background Tumors contain a functional subpopulation of cells that exhibit stem cell
properties. These cells, named cancer stem cells (CSCs), play significant roles in the …
properties. These cells, named cancer stem cells (CSCs), play significant roles in the …
The role of extracellular vesicles in the transfer of drug resistance competences to cancer cells
CPR Xavier, DC Belisario, R Rebelo, YG Assaraf… - Drug Resistance …, 2022 - Elsevier
Drug resistance remains a major hurdle to successful cancer treatment, being accountable
for approximately 90% of cancer-related deaths. In the past years, increasing attention has …
for approximately 90% of cancer-related deaths. In the past years, increasing attention has …