P21 facilitates macrophage chemotaxis by promoting CCL7 in the lung epithelial cell lines treated with radiation and bleomycin

X Liu, L Zeng, Y Zhou, X Zhao, L Zhu, J Zhang… - Journal of Translational …, 2023 - Springer
Abstract Background Interstitial lung diseases (ILDs) can be induced and even exacerbated
by radiotherapy in thoracic cancer patients. The roles of immune responses underlying the …

Utilizing MRI, [18F]FDG-PET and [89Zr]Zr-DFO-28H1 FAP-PET tracer to assess inflammation and fibrogenesis in a reproducible lung injury rat model: a multimodal …

M Boswinkel, R Raavé, A Veltien… - Frontiers in Nuclear …, 2023 - frontiersin.org
Objective Accurate imaging biomarkers that indicate disease progression at an early stage
are highly important to enable timely mitigation of symptoms in progressive lung disease. In …

Pulmonary toxicity in driver gene positive non-small cell lung cancer therapy

YP Zhao, Y Long - Current Medical Research and Opinion, 2022 - Taylor & Francis
Molecular targeted therapy significantly improved the therapeutic efficacy in non-small cell
lung cancer (NSCLC) patients with driver gene mutations but also with new toxicity profiles …

Radiolabeled GPVI-Fc for PET imaging of multiple extracellular matrix fibers: a new look into pulmonary fibrosis progression

S Isser, A Maurer, G Reischl, M Schaller… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Invariably fatal and with a particularly fast progression, pulmonary fibrosis (PF) is currently
devoid of curative treatment options. Routine clinical diagnosis relies on breathing tests and …

[HTML][HTML] Semi-automated micro-computed tomography lung segmentation and analysis in mouse models

JD Luisi, JL Lin, LF Ochoa, RJ McAuley, MG Tanner… - MethodsX, 2023 - Elsevier
Computed Tomography (CT) is a standard clinical tool utilized to diagnose known lung
pathologies based on established grading methods. However, for preclinical trials and …

Chronic progression of lung cancer recurrence after surgery: warning role of postoperative pneumonia

D Lin, J Zhu, X Xu, K Xiao, X Wen, Q Zheng… - Cancer Management …, 2021 - Taylor & Francis
Purpose The association between the process of postoperative pneumonia and lung cancer
recurrence remains elusive in lung cancer surgery. Herein, the association between …

Commentary: Imaging Biomarkers and Pathobiological Profiling in a Rat Model of Drug-Induced Interstitial Lung Disease (DIILD) Induced by Bleomycin

SI Sinis, SG Zarogiannis - Frontiers in Physiology, 2021 - frontiersin.org
Drug-induced interstitial lung disease (DIILD) is a clinical entity bearing significant morbidity
and mortality that presents with non-specific symptoms, more frequently cough, dyspnea …