[HTML][HTML] The role of the ECM in lung cancer dormancy and outgrowth

AL Parker, TR Cox - Frontiers in oncology, 2020 - frontiersin.org
The dissemination of tumor cells to local and distant sites presents a significant challenge in
the clinical management of many solid tumors. These cells may remain dormant for months …

[HTML][HTML] The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability

N Zhang, Y Shen, H Li, Y Chen, P Zhang… - … & molecular medicine, 2022 - nature.com
Abstract N6-methyladenosine (m6A) is the most abundant posttranscriptional modification of
mRNA in eukaryotes. Recent evidence suggests that dysregulated m6A-associated proteins …

[HTML][HTML] LncRNA LINC00460 promotes EMT in head and neck squamous cell carcinoma by facilitating peroxiredoxin-1 into the nucleus

Y Jiang, W Cao, K Wu, X Qin, X Wang, Y Li… - Journal of Experimental …, 2019 - Springer
Abstract Background The lncRNA LINC00460 plays crucial roles in several epithelial
cancers, although its mechanisms of action differ greatly in different cellular contexts. In this …

[HTML][HTML] RHOV promotes lung adenocarcinoma cell growth and metastasis through JNK/c-Jun pathway

D Zhang, Q Jiang, X Ge, Y Shi, T Ye, Y Mi… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Lung adenocarcinoma (LUAD) is a common type of lung cancer with high frequent
metastasis and a high death rate. However, genes responsible for LUAD metastasis are still …

[HTML][HTML] Promoter methylation-regulated miR-145-5p inhibits laryngeal squamous cell carcinoma progression by targeting FSCN1

W Gao, C Zhang, W Li, H Li, J Sang, Q Zhao, Y Bo… - Molecular therapy, 2019 - cell.com
Laryngeal squamous cell carcinoma (LSCC) is a common form of head and neck cancer
with poor prognosis. However, the mechanism underlying the pathogenesis of LSCC …

[HTML][HTML] Regulator of chromosome condensation 2 modulates cell cycle progression, tumorigenesis, and therapeutic resistance

K Guo, C Zhao, B Lang, H Wang, H Zheng… - Frontiers in molecular …, 2021 - frontiersin.org
Accurate regulation of cell cycle is important for normal tissue development and
homeostasis. RCC2 (Regulator of Chromosome Condensation 2) play a role as …

Overexpression of KIF20A confers malignant phenotype of lung adenocarcinoma by promoting cell proliferation and inhibiting apoptosis

X Zhao, L Zhou, X Li, J Ni, P Chen, R Ma, J Wu… - Cancer …, 2018 - Wiley Online Library
Increasing studies showed that kinesin family member 20A (KIF20A) was overexpessed in
several types of cancer, and its overexpression correlated with the oncogenesis and …

BRD4 drives esophageal squamous cell carcinoma growth by promoting RCC2 expression

Q Wu, F Liu, M Ge, KV Laster, L Wei, R Du, M Jiang… - Oncogene, 2022 - nature.com
The low survival rate of esophageal squamous cell carcinoma patients is primarily attributed
to technical limitations and a lack of insight regarding the molecular mechanisms …

[HTML][HTML] LncRNA LCPAT1 mediates smoking/particulate matter 2.5-induced cell autophagy and epithelial-mesenchymal transition in lung cancer cells via RCC2

H Lin, X Zhang, N Feng, R Wang, W Zhang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Ecological studies have shown that air pollution and prevalence of
cigarette smoking are positively correlated. Evidence also suggests a synergistic effect of …

miR-31-5p modulates cell progression in lung adenocarcinoma through TNS1/p53 axis

C Zhu, S Wang, M Zheng, Z Chen, G Wang… - Strahlentherapie und …, 2022 - Springer
Objective To clarify the modulatory mechanism of miR-31-5p in lung adenocarcinoma
(LUAD) progression in vivo and in vitro. Methods The Cancer Genome Atlas (TCGA) …