Firing activity of external globus pallidus (GPe) is crucial for motor control and is severely
perturbed in dystonia, a movement disorder characterized by involuntary, repetitive muscle …

Abstract Study Objectives Sleep and wake are opposing behavioral states controlled by the
activity of specific neurons that need to be located and mapped. To better understand how a …

Excessive oscillatory activity across basal ganglia (BG) nuclei in the β frequencies (12–30
Hz) is a hallmark of Parkinson's disease (PD). While the link between oscillations and …

Neurons in the external globus pallidus (GPe) are autonomous pacemakers, but their
spontaneous firing is continually perturbed by synaptic input. Because GPe neurons fire …

The mammalian brain is composed of diverse, specialized cell populations, few of which we
fully understand. To more systematically ascertain and learn from cellular specializations in …

Unitary pallido-nigral synaptic currents were measured using optogenetic stimulation, which
activated up to three unitary synaptic inputs to each substantia nigra pars reticulata (SNr) …

Although ethanol is one of the most widely used drugs, we still lack a full understanding of
which neuronal subtypes are affected by this drug. Pacemaker neurons exert powerful …

Abstract The DREADD (Designer Receptors Exclusively Activated by Designer Drugs)
technique is a new chemogenetic approach allowing for selective and remote control of …

Kernicterus is a serious complication of hyperbilirubinemia, caused by neuronal injury due
to excessive unconjugated bilirubin (UCB) in specific brain areas. This injury induced by this …

Dopamine neurotransmission is suspected to play important physiological roles in multiple
sparsely innervated brain nuclei, but there has not been a means to measure synaptic …