[PDF][PDF] The translational challenges of precision oncology

O Pich, C Bailey, TBK Watkins, S Zaccaria… - Cancer Cell, 2022 - cell.com
The translational challenges in the field of precision oncology are in part related to the
biological complexity and diversity of this disease. Technological advances in genomics …

[HTML][HTML] Strategies to control hepatitis B: Public policy, epidemiology, vaccine and drugs

S Locarnini, A Hatzakis, DS Chen, A Lok - Journal of hepatology, 2015 - Elsevier
The last 50 years of hepatitis B research has resulted in the development of effective
screening assays for surveillance, vaccines for prevention and antiviral drugs that …

Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates

JR Francica, BJ Flynn, KE Foulds, AT Noe… - Science translational …, 2021 - science.org
Adjuvanted soluble protein vaccines have been used extensively in humans for protection
against various viral infections based on their robust induction of antibody responses. Here …

[图书][B] Guidelines for the prevention care and treatment of persons with chronic hepatitis B infection: Mar-15

World Health Organization - 2015 - books.google.com
These are the first World Health Organization (WHO) guidelines for the prevention care and
treatment of persons living with CHB infection and complement similar recent published …

Virologic factors associated with failure to passive–active immunoprophylaxis in infants born to HBsAg‐positive mothers

H Zou, Y Chen, Z Duan, H Zhang… - Journal of viral …, 2012 - Wiley Online Library
In infants born to hepatitis B surface antigen (HBsAg)–positive mothers, failure after passive–
active immunization still occurs. The role of maternal hepatitis B DNA level and other risk …

Mother-to-infant transmission of hepatitis B virus infection: significance of maternal viral load and strategies for intervention

WH Wen, MH Chang, LL Zhao, YH Ni, HY Hsu… - Journal of …, 2013 - Elsevier
BACKGROUND & AIMS: Immunoprophylaxis reduces but does not completely eradicate
hepatitis B virus (HBV) transmission. This prospective study aims at assessing the rate and …

Effects of maternal screening and universal immunization to prevent mother-to-infant transmission of HBV

HL Chen, LH Lin, FC Hu, JT Lee, WT Lin, YJ Yang… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Mother-to-infant transmission is the major cause of hepatitis B virus
(HBV) infection among immunized children. There has been much debate about screening …

Development of the CpG adjuvant 1018: a case study

JD Campbell - Vaccine adjuvants: methods and protocols, 2017 - Springer
The development of aluminum salts (alum) as vaccine adjuvants was an empirical process
with little understanding of the mechanism of action and, with decades of use, it has become …

Hepatitis B vaccines

JW Ward, P Van Damme - Hepatitis B Virus and Liver Disease, 2018 - Springer
Since 1982, safe and effective hepatitis B virus (HBV) vaccines have been commercially
available first derived from plasma of HBV infected persons and later from yeast cells using …

[HTML][HTML] Viral hepatitis: Milestones, unresolved issues, and future goals

P Torre, A Aglitti, M Masarone… - World journal of …, 2021 - ncbi.nlm.nih.gov
In this review the current overall knowledge on hepatitis A, B, C, D, and E will be discussed.
These diseases are all characterized by liver inflammation but have significant differences in …