Microbiota, Tryptophan and aryl hydrocarbon receptors as the target triad in Parkinson's disease—A narrative review

P Iwaniak, M Owe-Larsson, EM Urbańska - International Journal of …, 2024 - mdpi.com
In the era of a steadily increasing lifespan, neurodegenerative diseases among the elderly
present a significant therapeutic and socio-economic challenge. A properly balanced diet …

Nicotinic Acetylcholine Receptors in Glial Cells as Molecular Target for Parkinson's Disease

ÉN Soares, ACS Costa, GJ Ferrolho, RP Ureshino… - Cells, 2024 - mdpi.com
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
resting tremor, bradykinesia, rigidity, and postural instability that also includes non-motor …

Evidence for prodromal changes in neuronal excitability and neuroinflammation in the hippocampus in young alpha-synuclein (A30P) transgenic mice

I Al-Musawi, BH Dennis, GJ Clowry… - Frontiers in …, 2024 - frontiersin.org
Introduction Neuronal hyperexcitability and neuroinflammation are thought to occur at early
stages in a range of neurodegenerative diseases. Neuroinflammation, notably activation of …

A Drosophila model for mechanistic investigation of tau protein spread

K Bankapalli, RE Thomas, ES Vincow, G Milstein… - bioRxiv, 2024 - biorxiv.org
Brain protein aggregates are a hallmark of neurodegenerative disease. Previous work
indicates that specific protein components of these aggregates are toxic, including tau in …

Amiloidinių baltymų α-sinukleino ir S100A9 neurotoksinio poveikio mechanizmo mikroglijos ląstelėms tyrimas

J Gružaitė - 2024 - epubl.ktu.edu
Abstract [eng] Over the last few years, various studies have expanded our knowledge of the
molecular mechanisms underlying the pathogenesis of neurodegenerative diseases and …

[PDF][PDF] Ibtisam Al-Musawi, Bethany H. Dennis, Gavin J. Clowry and Fiona EN LeBeau

C Kim, EJ Bae, M Zilberter - researchgate.net
Results: We found an interesting biphasic change in the expression of c-Fos in AP mice with
high expression at month, consistent with early onset of hyperexcitability, but lower …