[HTML][HTML] Cellular and molecular evidence of multiple sclerosis diagnosis and treatment challenges

Z Khan, GD Gupta, S Mehan - Journal of clinical medicine, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease that impacts the central nervous
system and can result in disability. Although the prevalence of MS has increased in India …

[HTML][HTML] Interaction of heavy metal lead with gut microbiota: implications for autism spectrum disorder

Y Tizabi, S Bennani, N El Kouhen, B Getachew… - Biomolecules, 2023 - mdpi.com
Autism Spectrum Disorder (ASD), a neurodevelopmental disorder characterized by
persistent deficits in social interaction and communication, manifests in early childhood and …

[HTML][HTML] Ellagic acid effects on disease severity, levels of cytokines and T-bet, RORγt, and GATA3 genes expression in multiple sclerosis patients: a multicentral-triple …

S Jafari Karegar, N Aryaeian, G Hajiluian… - Frontiers in …, 2023 - frontiersin.org
Background Multiple sclerosis (MS) is a chronic autoimmune disease. Ellagic acid is a
natural polyphenol and affects the fate of neurons through its anti-inflammatory and …

[HTML][HTML] The effects of intermittent fasting for patients with multiple sclerosis (MS): a systematic review

X Lin, S Wang, Y Gao - Frontiers in Nutrition, 2024 - frontiersin.org
Some studies have investigated the impact of intermittent fasting (IF) for patients with
multiple sclerosis (MS). We aimed to conduct a comprehensive systematic review to analyze …

Immune System Dysregulation in the Progression of Multiple Sclerosis: Molecular Insights and Therapeutic Implications

Z Khan, S Mehan, GD Gupta, AS Narula - Neuroscience, 2024 - Elsevier
Multiple sclerosis (MS), a prevalent neurological disorder, predominantly affects young
adults and is characterized by chronic autoimmune activity. The study explores the immune …

Matrine exerts its neuroprotective effects by modulating multiple neuronal pathways

S Chhabra, S Mehan - Metabolic Brain Disease, 2023 - Springer
Recent evidence suggests that misfolding, clumping, and accumulation of proteins in the
brain may be common causes and pathogenic mechanism for several neurological …

Activated intestinal microbiome-associated tryptophan metabolism upregulates aryl hydrocarbon receptor to promote osteoarthritis in a rat model

L Chen, Z Huang, Q Li, C Chen, Y Luo… - International …, 2023 - Elsevier
Objective To evaluate the role of aryl hydrocarbon receptor in the pathogenesis of
osteoarthritis (OA) and its association with intestinal microbiome-related tryptophan …

[HTML][HTML] Kombucha: Challenges for health and mental health

P Batista, M Rodrigues Penas, C Vila-Real, M Pintado… - Foods, 2023 - mdpi.com
Background: Increasing research into probiotics is showing potential benefits for health in
general and mental health in particular. Kombucha is a recent beverage and can be …

[HTML][HTML] The gut-brain axis in autoimmune diseases: Emerging insights and therapeutic implications

MM Khawar Sr, S Ijaz, P Goyal, D Kandambige… - Cureus, 2023 - ncbi.nlm.nih.gov
The gut-brain axis (GBA) is a two-way communication system that is influenced by signals
from the nervous system, hormones, metabolism, the immune system, and microbes. The …

Guggulsterone Selectively Modulates STAT-3, mTOR, and PPAR-Gamma Signaling in a Methylmercury-Exposed Experimental Neurotoxicity: Evidence from CSF …

S Kumar, S Mehan, Z Khan, G Das Gupta… - Molecular …, 2024 - Springer
Amyotrophic lateral sclerosis (ALS) is a paralytic disease that damages the brain and spinal
cord motor neurons. Several clinical and preclinical studies have found that methylmercury …