TRAIL receptor targeting therapies for non-small cell lung cancer: current status and perspectives

JH Stegehuis, LHAM de Wilt, EGE de Vries… - Drug resistance …, 2010 - Elsevier
Non-small cell lung cancer (NSCLC) is a common and often fatal malignancy, diagnosed at
an advanced stage in more than half of the cases. Chemo-resistance remains a major …

Targeted therapies for non–small cell lung cancer: an evolving landscape

SK Pal, RA Figlin, K Reckamp - Molecular cancer therapeutics, 2010 - AACR
Over the past decade, a multitude of targeted agents have been explored in the treatment of
advanced non–small cell lung cancer (NSCLC). Thus far, two broad classes of agents have …

Effect of celecoxib on survival in patients with advanced non-small cell lung cancer: a double blind randomised clinical phase III trial (CYCLUS study) by the Swedish …

A Koch, B Bergman, E Holmberg, C Sederholm… - European journal of …, 2011 - Elsevier
Background Increased expression of cyclooxygenase-2 (COX-2) is common in non-small
cell lung cancer (NSCLC) and has been associated with poor prognosis. Experimental and …

Novel Targeted Agents and Radiopharmaceuticals in Lung Cancer

MJ Edelman, N Ijaz - Advances in Radiation Oncology in Lung Cancer, 2011 - Springer
The use of chemotherapy in addition to radiation has unquestionably improved outcomes in
both small cell and non-small cell lung cancer. However, as in advanced disease, a plateau …

[HTML][HTML] Clinical Aspects of Inflammation in Non-small Cell Lung Cancer

A Koch - 2011 - diva-portal.org
Lung cancer is the most common cause of cancer death worldwide, with about 1.2 million
deaths every year. In Sweden, about 3500 new cases are diagnosed every year. The …

Apricoxib

MJ Edelman - Drugs of the Future, 2011 - access.portico.org
SUMMARY Overexpression of cyclooxygenase-2 (COX-2) has been implicated as a tumor-
initiating and-promoting event for a number of common solid tumors, including lung, breast …

Non-small cell lung cancer–ASCO 2009

S Rothschild, O Gautschi - memo-Magazine of European Medical …, 2009 - Springer
From May 29 to June 2, the American Society of Clinical Oncology (ASCO) held its annual
meeting in Orlando, Florida (USA). The meeting was themed “personalizing cancer care” …