An evolutionary strategy for a stealthy intracellular Brucella pathogen

A Martirosyan, E Moreno, JP Gorvel - Immunological reviews, 2011 - Wiley Online Library
Brucella is an intracellular bacterial pathogen that causes abortion and infertility in mammals
and leads to a debilitating febrile illness that can progress into a long lasting disease with …

[HTML][HTML] Cell-mediated immunity in human brucellosis

P Skendros, G Pappas, P Boura - Microbes and infection, 2011 - Elsevier
Brucella can parasitize within human antigen-presenting cells modifying phagocytosis,
phagolysosome fusion, antigen presentation, cytokine secretion, and apoptosis. Subversion …

A review of the immunopathogenesis of Brucellosis

O Amjadi, A Rafiei, M Mardani, P Zafari… - Infectious …, 2019 - Taylor & Francis
Brucellosis, caused by the intracellular pathogens Brucella, is one of the major zoonotic
infections. Considering the economic burden, its prevalence has been a health concern …

Cytokine Polymorphisms and Severity of Tubal Damage in Women with Chlamydia-Associated Infertility

H Öhman, A Tiitinen, M Halttunen… - The journal of …, 2009 - academic.oup.com
Chronic inflammation induced by Chlamydia trachomatis can lead to tubal factor infertility
(TFI). To investigate the genetic basis of chlamydial TFI and various manifestations of tubal …

Association between polymorphisms of cytokine genes and brucellosis: A comprehensive systematic review and meta-analysis

P Zafari, A Zarifian, R Alizadeh-Navaei, M Taghadosi… - Cytokine, 2020 - Elsevier
Objective Owing to involvement of host genetic factors in susceptibility to brucellosis
infection and its outcome, this study aimed to carry out a comprehensive systematic review …

Polymorphism of cytokine and innate immunity genes associated with bovine brucellosis in cattle

O Prakash, A Kumar, A Sonwane, R Rathore… - Molecular biology …, 2014 - Springer
Genetic susceptibility to brucellosis is multifactorial, and it is known that impairment of the
immune system could contribute to risk for getting brucellosis. The aim of the study was to …

[PDF][PDF] TNF-alpha, TGF-beta, IL-10, IL-6 and IFN-gamma gene polymorphisms as risk factors for brucellosis

I Karaoglan, S Pehlivan, M Namiduru… - New …, 2009 - newmicrobiologica.org
Brucella spp. are gram-negative, facultative and intracellular bacteria that can cause chronic
zoonotic infections in humans (Young, 2005). The organism can be transmitted from animals …

The gene-immune-behavioral pathway: Gamma-interferon (IFN-γ) simultaneously coordinates susceptibility to infectious disease and harm avoidance behaviors

J MacMurray, DE Comings, V Napolioni - Brain, Behavior, and Immunity, 2014 - Elsevier
Cytokine gene variants are known to influence both infectious disease susceptibility and
harm-avoidant behaviors, suggesting that these risk variants may be pleiotropically linked to …

Interferon‐gamma and interleukin‐12 gene polymorphisms and their relation to aggressive and chronic periodontitis and key periodontal pathogens

S Reichert, HKG Machulla, J Klapproth… - Journal of …, 2008 - Wiley Online Library
Background: The gene polymorphisms interferon‐gamma (IFN‐γ) 874 T/A and interleukin
(IL)‐12 1188 A/C have been associated with the altered production of cytokines. Therefore …

Effect of anti-inflammatory (IL-4, IL-10) cytokine genes in relation to risk of cervical carcinoma

M Shekari, DM Kordi-Tamandani… - American journal of …, 2012 - journals.lww.com
Objectives: Cervical cancer is rated the second most common malignant tumor globally and
is etiologically linked to human papillomavirus infection. Interleukin-4 (IL-4) and IL-10 are …