Oxidative stress in autism spectrum disorder—current progress of mechanisms and biomarkers

X Liu, J Lin, H Zhang, NU Khan, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a type of neurodevelopmental disorder that has been
diagnosed in an increasing number of children around the world. Existing data suggest that …

The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models

L Mapelli, T Soda, E D'Angelo, F Prestori - International journal of …, 2022 - mdpi.com
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …

The pivotal role of JAK/STAT and IRS/PI3K signaling pathways in neurodegenerative diseases: Mechanistic approaches to polyphenols and alkaloids

L Kooshki, SN Zarneshan, S Fakhri, SZ Moradi… - Phytomedicine, 2023 - Elsevier
Abstract Background Neurodegenerative diseases (NDDs) are characterized by progressive
neuronal dysfunctionality which results in disability and human life-threatening events. In …

Role of oxidative stress and antioxidants in autism

T Manivasagam, S Arunadevi, MM Essa… - … food intervention and …, 2020 - Springer
Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders
with poorly understood etiology that are defined exclusively on the basis of behavioral …

Potential therapeutic effects of curcumin mediated by JAK/STAT signaling pathway: a review

M Ashrafizadeh, H Rafiei… - Phytotherapy …, 2020 - Wiley Online Library
Curcumin is a naturally occurring nutraceutical compound with a number of therapeutic and
biological activities such as antioxidant, anti‐inflammatory, anti‐diabetic, antitumor, and …

Systemic maternal inflammation promotes ASD via IL-6 and IFN-γ

D Majerczyk, EG Ayad, KL Brewton, P Saing… - Bioscience …, 2022 - portlandpress.com
Autism spectrum disorder (ASD) is a neurological disorder that manifests during early
development, impacting individuals through their ways of communicating, social behaviors …

Combining network pharmacology, RNA-seq, and metabolomics strategies to reveal the mechanism of Cimicifugae Rhizoma-Smilax glabra Roxb herb pair for the …

XQ Hu, C Qi, F Feng, Y Wang, TT Di, YJ Meng, Y Wang… - Phytomedicine, 2022 - Elsevier
Background Psoriasis is a prevalent chronic inflammatory skin condition marked by immune
cell infiltration and keratinocyte abnormal proliferation. Cimicifugae Rhizoma-Smilax glabra …

Resveratrol eliminates cancer stem cells of osteosarcoma by STAT3 pathway inhibition

L Peng, D Jiang - PLoS One, 2018 - journals.plos.org
Resveratrol shows potent anti-tumor therapeutic properties in various tumors. However, the
exact effect of resveratrol on osteosarcoma cells, especially cancer stem cells, remains …

Role of JAK-STAT and PPAR-gamma signalling modulators in the prevention of autism and neurological dysfunctions

R Khera, S Mehan, S Kumar, P Sethi, S Bhalla… - Molecular …, 2022 - Springer
The Janus-kinase (JAK) and signal transducer activator of transcription (STAT) signalling
pathways regulate gene expression and control various factors involved in normal …

[HTML][HTML] Palmitoylethanolamide counteracts autistic-like behaviours in BTBR T+ tf/J mice: Contribution of central and peripheral mechanisms

C Cristiano, C Pirozzi, L Coretti, G Cavaliere… - Brain, behavior, and …, 2018 - Elsevier
Autism spectrum disorders (ASD) are a group of heterogeneous neurodevelopmental
conditions characterized by impaired social interaction, and repetitive stereotyped …