Fungi or bacteria that produce secondary metabolites often have the potential to bring up
various compounds from a single strain. The molecular basis for this well‐known …

While the oceans cover more than 70% of the Earth's surface, marine derived microbial
natural products have been largely unexplored. The marine environment is a habitat for …

Myxobacteria are gram-negative bacteria which are most noted for their ability to form
fruiting bodies upon starvation. Within the last two decades, they increasingly gained …

The massive surge in genome sequencing projects has opened our eyes to the overlooked
biosynthetic potential and metabolic diversity of microorganisms. While traditional …

Curacin A (1) is a potent cancer cell toxin obtained from strains of the tropical marine
cyanobacterium Lyngbya majuscula found in Curaçao. Its structure is unique in that it …

Genomics has resulted in the deposition of a huge quantity of DNA sequence data from a
wide variety of organisms in publicly accessible databases. Such data can be exploited to …

Historically, nature has provided the source for the majority of the drugs in use today. More
than 20,000 microbial secondary metabolites have been described, but only a small …

Abstract “There's life in the old dog yet!” This adage also holds true for natural product
research. After the era of natural products was declared to be over, because of the …

Covering: up to the end of 2013 The in-depth analysis of secondary metabolomes of many
microbes offers tremendous opportunities for the discovery of novel natural products which …

In this article, we briefly review the potential of myxobacteria as 'natural product factories' by
highlighting results from the recently sequenced myxobacterial model strain Myxococcus …