Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …

Reactive oxygen and nitrogen species (RONS) are produced by several endogenous and
exogenous processes, and their negative effects are neutralized by antioxidant defenses …

Statins are a family of drugs that are used for treating hyperlipidaemia with a recognized
capacity to prevent cardiovascular disease events. They inhibit β‐hydroxy β‐methylglutaryl …

Cellular senescence is defined as irreversible cell cycle arrest caused by various processes
that render viable cells non-functional, hampering normal tissue homeostasis. It has many …

World population growth and aging are posing unprecedented challenges in sustaining the
health of 9.1 billion people that will be occupying the planet by 2050. Although …

Dysfunction of the oxidative phosphorylation (OXPHOS) system is a major cause of human
disease and the cellular consequences are highly complex. Here, we present comparative …

The burden of cardiovascular and metabolic diseases is increasing with every year.
Although the management of these conditions has improved greatly over the years, it is still …

Coenzyme Q10 (CoQ10) is an essential cofactor in oxidative phosphorylation (OXPHOS),
present in mitochondria and cell membranes in reduced and oxidized forms. Acting as an …

Abstract Coenzyme Q 10 (CoQ 10) is an essential component of the mitochondrial electron
transport chain. It is also an antioxidant in cellular membranes and lipoproteins. All cells …

Alzheimer's disease (AD) is characterized by cognitive inability manifested due to the
accumulation of β-amyloid, formation of hyper phosphorylated neurofibrillary tangles, and a …