Lung cancer is a major global health problem, as it is the leading cause of cancer-related
deaths worldwide. Major advances in the identification of key mutational alterations have led …

The tumor microenvironment (TME) represents a milieu that enables tumor cells to acquire
the hallmarks of cancer. The TME is heterogeneous in composition and consists of cellular …

The development of a simple and fast cancer detection method is crucial since early
diagnosis is a key factor in increasing survival rates for lung cancer patients. Among several …

Skeletal muscle atrophy with high prevalence can induce weakness and fatigability and
place huge burden on both health and quality of life. During skeletal muscle degeneration …

Nonsmall cell lung cancer (NSCLC) is a leading cause of global cancer mortality. Recently,
combinatorial treatment approaches have shown promise as they better address tumor …

Background/Aims: The effects of glycyrrhizin treatment in lung cancer remain undetermined,
despite extensive studies of the anti-tumor activities of glycyrrhizin. Methods: Lung …

Abstract Cyclooxygenase-2 (COX-2) has been implicated in cell invasion in non-small-cell
lung cancer (NSCLC). However, the mechanism is unclear. The present study investigated …

The prostaglandin-endoperoxide synthase-2 (PTGS2) plays essential roles in diverse
pathological process. Although recent studies implied that PTGS2 was closely related with …

Lung cancer causes 1.4 million deaths annually. In the search for functional foods as
complementary therapies against lung cancer, the immuno-stimulatory properties of the …

AZB-IMC2 was developed as a COX-2 specific probe that exhibited a brighter fluorescence
signal in cancer cells that overexpress COX-2 compared to normal cells. Oxidative stress …