Ferroptosis is a new form of regulated cell death (RCD) driven by iron-dependent lipid
peroxidation, which is morphologically and mechanistically distinct from other forms of RCD …

Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …

Background Ferroptosis is a recently identified iron-dependent form of cell death as a result
of increased reactive oxygen species (ROS) and lipid peroxidation. In this study, we …

Sepsis-associated encephalopathy (SAE) is a common complication of severe sepsis. Irisin
is a novel exercise-induced myokine involved in the regulation of adipose browning and …

Cerebrovascular disease and its risk factors cause persistent decrease of cerebral blood
flow, chronic cerebral hypoperfusion (CCH) is the major foundation of vascular cognitive …

Iron metabolism disturbances play an important role in early brain injury (EBI) after
subarachnoid hemorrhage (SAH), and hepcidin largely influences iron metabolism …

Objective Ferroptosis is indicated in cardiovascular diseases. Given the prominent role of
mitophagy in the governance of ferroptosis and our recent finding for FUN14 domain …

Puerarin was shown to exert anti-oxidative and anti-ferroptosis effects in multiple diseases.
The goal of this study was to explore the neuroprotective effect of puerarin on early brain …

Traumatic brain injury (TBI) can lead to disability or devastating consequences with few
established treatments. Although ferroptosis has been shown to be involved in TBI, the …

Stroke is a common and serious nervous system disease caused by the rupture or blockage
of the cardiovascular system. It causes millions of deaths and disabilities every year, which …