[HTML][HTML] Recent Developments in Methicillin-Resistant Staphylococcus aureus (MRSA) Treatment: A Review

P Nandhini, P Kumar, S Mickymaray, AS Alothaim… - Antibiotics, 2022 - mdpi.com
Staphylococcus aureus (S. aureus) is a Gram-positive bacterium that may cause life-
threatening diseases and some minor infections in living organisms. However, it shows …

[HTML][HTML] Vancomycin Resistance in Enterococcus and Staphylococcus aureus

G Li, MJ Walker, DMP De Oliveira - Microorganisms, 2022 - mdpi.com
Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus are both common
commensals and major opportunistic human pathogens. In recent decades, these bacteria …

Infective Endocarditis After Transcatheter Aortic Valve Replacement: JACC State-of-the-Art Review

D Del Val, V Panagides, CA Mestres, JM Miró… - Journal of the American …, 2023 - jacc.org
Infective endocarditis (IE) is a rare but serious complication following transcatheter aortic
valve replacement (TAVR). Despite substantial improvements in the TAVR procedure (less …

[HTML][HTML] The promising potential of reverse vaccinology-based next-generation vaccine development over conventional vaccines against antibiotic-resistant bacteria

K Khalid, CL Poh - Vaccines, 2023 - mdpi.com
The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR)
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …

[HTML][HTML] Critical Assessment of the Prospects of Quorum-Quenching Therapy for Staphylococcus aureus Infection

M Otto - International Journal of Molecular Sciences, 2023 - mdpi.com
Staphylococcus aureus is an important pathogen that causes a high number of infections
and is one of the leading causes of death in hospitalized patients. Widespread antibiotic …

Expanding antibiotic, vaccine, and diagnostics development and access to tackle antimicrobial resistance

R Laxminarayan, I Impalli, R Rangarajan, J Cohn… - The Lancet, 2024 - thelancet.com
The increasing number of bacterial infections globally that do not respond to any available
antibiotics indicates a need to invest in—and ensure access to—new antibiotics, vaccines …

Efficacy of a 4-Antigen Staphylococcus aureus Vaccine in Spinal Surgery: The STaphylococcus aureus suRgical Inpatient Vaccine Efficacy (STRIVE) Randomized …

H Hassanzadeh, J Baber, E Begier… - Clinical Infectious …, 2023 - academic.oup.com
Background Staphylococcus aureus is a global pathogen that is frequently responsible for
healthcare-associated infections, including surgical site infections (SSIs). Current infection …

[HTML][HTML] Global, regional, and national incidence and mortality burden of non-COVID-19 lower respiratory infections and aetiologies, 1990–2021: a systematic analysis …

RG Bender, SB Sirota, LR Swetschinski… - The Lancet Infectious …, 2024 - thelancet.com
Summary Background Lower respiratory infections (LRIs) are a major global contributor to
morbidity and mortality. In 2020–21, non-pharmaceutical interventions associated with the …

Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

[HTML][HTML] Staphylococcus aureus—A Known Opponent against Host Defense Mechanisms and Vaccine Development—Do We Still Have a Chance to Win?

U Wójcik-Bojek, B Różalska, B Sadowska - International journal of …, 2022 - mdpi.com
The main purpose of this review is to present justification for the urgent need to implement
specific prophylaxis of invasive Staphylococcus aureus infections. We emphasize the …