Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

RT Walton, KA Christie, MN Whittaker, BP Kleinstiver - Science, 2020 - science.org
Manipulation of DNA by CRISPR-Cas enzymes requires the recognition of a protospacer-
adjacent motif (PAM), limiting target site recognition to a subset of sequences. To remove …

[HTML][HTML] Unconstrained Genome Targeting with near-PAMless Engineered CRISPR-Cas9 Variants

RT Walton, KA Christie, MN Whittaker… - Science (New York …, 2020 - ncbi.nlm.nih.gov
Manipulation of DNA by CRISPR-Cas enzymes requires the recognition of a protospacer
adjacent motif (PAM), limiting target site recognition to a subset of sequences. To remove …

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

RT Walton, KA Christie, MN Whittaker… - Science, 2020 - ui.adsabs.harvard.edu
Manipulation of DNA by CRISPR-Cas enzymes requires the recognition of a protospacer-
adjacent motif (PAM), limiting target site recognition to a subset of sequences. To remove …

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

RT Walton, KA Christie, MN Whittaker, BP Kleinstiver - paper.sciencenet.cn
AbstractManipulation of DNA by CRISPR-Cas enzymes requires the recognition of a
protospacer adjacent motif (PAM), limiting target site recognition to a subset of sequences …

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

RT Walton, KA Christie, MN Whittaker… - … (New York, NY), 2020 - pubmed.ncbi.nlm.nih.gov
Manipulation of DNA by CRISPR-Cas enzymes requires the recognition of a protospacer-
adjacent motif (PAM), limiting target site recognition to a subset of sequences. To remove …

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

RT Walton, KA Christie, MN Whittaker, BP Kleinstiver - Science, 2020 - cir.nii.ac.jp
抄録< jats: title> A PAMless base editor</jats: title>< jats: p> CRISPR-Cas DNA base editing
typically requires a specific motif for targeting known as a protospacer-adjacent motif (PAM) …

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants.

RT Walton, KA Christie, MN Whittaker… - Science (New York …, 2020 - europepmc.org
Manipulation of DNA by CRISPR-Cas enzymes requires the recognition of a protospacer
adjacent motif (PAM), limiting target site recognition to a subset of sequences. To remove …