Identification and functional characterization of rat riboflavin transporter 2

S Yamamoto, K Inoue, K Ohta, R Fukatsu… - Journal of …, 2009 - academic.oup.com
We have newly identified rat riboflavin transporter 2 (rRFT2) and its human orthologue
(hRFT2), and carried out detailed functional characterization of rRFT2. The mRNA of rRFT2 …

Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1

A Yonezawa, S Masuda… - American Journal of …, 2008 - journals.physiology.org
Absorption of riboflavin is mediated by transporter (s). However, a mammalian riboflavin
transporter has yet to be identified. In the present study, the novel human and rat riboflavin …

[HTML][HTML] Functional characteristics of the human ortholog of riboflavin transporter 2 and riboflavin-responsive expression of its rat ortholog in the small intestine indicate …

M Fujimura, S Yamamoto, T Murata, T Yasujima… - The Journal of …, 2010 - Elsevier
Riboflavin transporter (RFT) 2 has recently been identified as a transporter that may be,
mainly based on the functional characteristics of its rat ortholog (rRFT2), involved in the …

[HTML][HTML] Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain

Y Yao, A Yonezawa, H Yoshimatsu, S Masuda… - The Journal of …, 2010 - Elsevier
We isolated cDNA coding a new human riboflavin transporter (hRFT) 3, which exhibits 86.7
and 44.1% amino acid identity with hRFT1 and hRFT2, respectively. It was predicted to have …

Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells

VS Subramanian, L Rapp… - American Journal of …, 2011 - journals.physiology.org
The water-soluble vitamin B2 (riboflavin, RF) is an essential micronutrient for normal cell
function and survival. Recent studies have identified a role for the human riboflavin …

[HTML][HTML] Differential expression of human riboflavin transporters-1,-2, and-3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake

VS Subramanian, SB Subramanya, L Rapp… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Transport of riboflavin (RF) across both the brush border membrane (BBM) and basolateral
membrane (BLM) of the polarized enterocyte occurs via specific carrier-mediated …

Novel riboflavin transporter family RFVT/SLC52: identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52

A Yonezawa, K Inui - Molecular aspects of medicine, 2013 - Elsevier
Riboflavin, a water-soluble vitamin also known as vitamin B2, is essential for normal cellular
functions. Riboflavin transporters play important roles in its homeostasis. Recently, three …

Molecular mechanisms mediating the adaptive regulation of intestinal riboflavin uptake process

VS Subramanian, A Ghosal, R Kapadia… - PLoS …, 2015 - journals.plos.org
The intestinal absorption process of vitamin B2 (riboflavin, RF) is carrier-mediated, and all
three known human RF transporters, ie, hRFVT-1,-2, and-3 (products of the SLC52A1, 2 & 3 …

Riboflavin transporter is finally identified

Y Moriyama - The Journal of Biochemistry, 2011 - academic.oup.com
Riboflavin or vitamin B2 is one of the constituents of energy drinks. Although this compound
is known to be absorbed in the intestine and that it circulates throughout the body and is …

The monocarboxylate transporter homolog Mch5p catalyzes riboflavin (vitamin B2) uptake in Saccharomyces cerevisiae

P Reihl, J Stolz - Journal of biological chemistry, 2005 - ASBMB
Riboflavin is a water-soluble vitamin (vitamin B 2) required for the production of the flavin
cofactors FMN and FAD. Mammals are unable to synthesize riboflavin and need a dietary …