The Vpr protein from HIV-1: distinct roles along the viral life cycle

E Le Rouzic, S Benichou - Retrovirology, 2005 - Springer
The genomes of human and simian immunodeficiency viruses (HIV and SIV) encode the
gag, pol and env genes and contain at least six supplementary open reading frames termed …

HIV-1 Vpr—a still “enigmatic multitasker”

CA Guenzel, C Hérate, S Benichou - Frontiers in microbiology, 2014 - frontiersin.org
Like other HIV-1 auxiliary proteins, Vpr is conserved within all the human (HIV-1, HIV-2) and
simian (SIV) immunodeficiency viruses. However, Vpr and homologous HIV-2, and SIV Vpx …

[PDF][PDF] Molecular biology of the human immunodeficiency virus accessory proteins

RA Subbramanian, EA Cohen - Journal of virology, 1994 - Am Soc Microbiol
The human immunodeficiency virus (HIV) is the causative agent of AIDS. HIV belongs to a
unique virus family, the Retroviridae, a group of small, enveloped, positive-strand RNA …

Human immunodeficiency virus type 1 Vpr: functions and molecular interactions

B Romani, S Engelbrecht - Journal of General Virology, 2009 - microbiologyresearch.org
Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) is an accessory protein
that interacts with a number of cellular and viral proteins. The functions of many of these …

[HTML][HTML] Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein.

LJ Zhao, S Mukherjee, O Narayan - Journal of Biological Chemistry, 1994 - Elsevier
vpr is an accessory gene of human immunodeficiency virus I (HIV-I). Although unnecessary
for viral replication in T cell lines, growing evidence suggests that it is essential for virus …

HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention

M Kogan, J Rappaport - Retrovirology, 2011 - Springer
The HIV protein, Vpr, is a multifunctional accessory protein critical for efficient viral infection
of target CD4+ T cells and macrophages. Vpr is incorporated into virions and functions to …

The role of Vpr in HIV-1 pathogenesis

JL Andersen, V Planelles - Current HIV research, 2005 - ingentaconnect.com
The HIV-1 vpr gene is conserved among the human (HIV-1, HIV-2) and simian
immunodeficiency viruses (SIV). HIV-1 vpr encodes a 96-amino acid, 14 kDa protein (Vpr) …

Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1

T Kino, GN Pavlakis - DNA and cell biology, 2004 - liebertpub.com
Vpr (Viral protein-R) of the Human Immunodeficiency Virus type-1 is a 14-kDa virion-
associated protein, conserved in HIV-1,-2 and the Simian Immunodeficiency Virus (SIV). Vpr …

Human Immunodeficiency Virus vpr Gene Encodes a Virion-Associated Protein

X Yuan, Z MATSUDA, M MATSUDA… - AIDS research and …, 1990 - liebertpub.com
The vpr gene of human immunodeficiency virus type 1 (HIV-1) is one of the seven accessory
genes that are believed to have roles in the virus replication cycle. We report here the …

Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency

DN Levy, Y Refaeli, DB Weiner - Journal of virology, 1995 - Am Soc Microbiol
The vpr gene product of human immunodeficiency virus (HIV) and simian immunodeficiency
virus is a virion-associated regulatory protein that has been shown using vpr mutant viruses …